Department of Ophthalmology, University of Florida-College of Medicine, Jacksonville, FL, USA.
Indian J Ophthalmol. 2011 Jan-Feb;59(1):47-8. doi: 10.4103/0301-4738.73712.
Retinal pigment epithelial (RPE) tear has been described to occur spontaneously, after laser photocoagulation and in recent times, after intravitreal injection of anti-vascular endothelial growth factor (VEGF) agents. In the latter case, the rapid contraction of the choroidal vascular membrane underneath a serous RPE detachment is believed to be the underlying cause. Preservation of good visual acuity after the occurrence of RPE tear with continued use of intravitreal VEGF agents has been reported. In this case report, we describe the occurrence of multiple RPE tears with the use of intravitreal bevacizumab and also correlate the preservation of visual acuity with features seen on spectral domain optical coherence tomography.
视网膜色素上皮 (RPE) 撕裂已被描述为自发发生，在激光光凝后，以及最近在玻璃体内注射抗血管内皮生长因子 (VEGF) 药物后发生。在后一种情况下，浆液性 RPE 脱离下的脉络膜血管膜的快速收缩被认为是潜在的原因。据报道，在继续使用玻璃体内 VEGF 药物后，RPE 撕裂发生后仍能保持良好的视力。在本病例报告中，我们描述了使用玻璃体内贝伐单抗引起的多处 RPE 撕裂，并通过光谱域光学相干断层扫描所见特征来关联视力的保留情况。
