用于即时检测的 TNFα、PCT 和 CRP 的多参数测定。
Multi-parameter determination of TNFα, PCT and CRP for point-of-care testing.
机构信息
Helmholtz Zentrum München-German Research Center for Environmental Health, Institute of Ecological Chemistry, Neuherberg, Oberschleissheim, Germany.
出版信息
Analyst. 2011 Feb 21;136(4):692-5. doi: 10.1039/c0an00699h. Epub 2010 Dec 15.
PMID:21157594
Abstract
A proof of concept for the simultaneous multi-parameter determination of three inflammation and sepsis parameters-TNFα, PCT and CRP-using a compact optical immunosensor is demonstrated. Harmonized assay conditions revealed standard curves with test midpoints (IC(50)) of 380 µg L(-1) for TNFα, 2300 µg L(-1) for PCT, and 2645 µg L(-1) for CRP.
摘要
利用紧凑型光学免疫传感器，证明了同时测定三种炎症和脓毒症参数（TNFα、PCT 和 CRP）的多参数测定的概念验证。协调的测定条件显示出标准曲线，TNFα 的测试中点（IC（50））为 380 µg L（-1），PCT 为 2300 µg L（-1），CRP 为 2645 µg L（-1）。
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