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隐匿性和不明原因的胃肠道出血:2009年的病因及诊断方法

Occult and obscure gastrointestinal bleeding: Causes and diagnostic approach in 2009.

作者信息

Bresci Giampaolo

机构信息

Giampaolo Bresci, UO Gastroenterrologia, AOUPisana, Pisa 56125, Italy.

出版信息

World J Gastrointest Endosc. 2009 Oct 15;1(1):3-6. doi: 10.4253/wjge.v1.i1.3.

Abstract

Gastrointestinal bleeding can be obscure or occult (OGIB), the causes and diagnostic approach will be discussed in this editorial. The evaluation of OGIB consists on a judicious search of the cause of bleeding, which should be guided by the clinical history and physical findings. The standard approach to patients with OGIB is to directly evaluate the gastrointestinal tract by endoscopy, abdominal computed tomography, angiography, radionuclide scanning, capsule endoscopy. The source of OGIB can be identified in 85%-90%, no bleeding sites will be found in about 5%-10% of cases. Even if the bleedings originating from the small bowel are not frequent in clinical practice (7.6% of all digestive haemorrhages, in our casuistry), they are notoriously difficult to diagnose. In spite of progress, however, a number of OGIB still remain problematic to deal with at present in the clinical context due to both the difficulty in exactly identifying the site and nature of the underlying source and the difficulty in applying affective and durable diagnostic approaches so no single technique has emerged as the most efficient way to evaluate OGIB.

摘要

胃肠道出血可能是隐匿性的(OGIB),本文将讨论其病因及诊断方法。OGIB的评估包括对出血原因进行审慎的排查,这应以临床病史和体格检查结果为指导。OGIB患者的标准评估方法是通过内镜检查、腹部计算机断层扫描、血管造影、放射性核素扫描、胶囊内镜直接评估胃肠道。OGIB的出血源在85%-90%的病例中可被确定,约5%-10%的病例找不到出血部位。即使小肠出血在临床实践中并不常见(在我们的病例中占所有消化道出血的7.6%),但众所周知,其诊断难度很大。然而,尽管取得了进展,但由于难以准确确定潜在出血源的部位和性质,以及难以应用有效且持久的诊断方法,目前在临床情况下仍有许多OGIB病例难以处理,因此尚未有一种单一技术成为评估OGIB的最有效方法。

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本文引用的文献

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Enteroscopy.小肠镜检查
Best Pract Res Clin Gastroenterol. 2008;22(5):789-811. doi: 10.1016/j.bpg.2008.05.005.
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Capsule endoscopy in neoplastic diseases.肿瘤疾病中的胶囊内镜检查
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Cost-effectiveness analysis of management strategies for obscure GI bleeding.不明原因胃肠道出血管理策略的成本效益分析
Gastrointest Endosc. 2008 Nov;68(5):920-36. doi: 10.1016/j.gie.2008.01.035. Epub 2008 Apr 14.
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The patient with recidivent obscure gastrointestinal bleeding.患有复发性隐匿性胃肠道出血的患者。
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