Hopf C, Beuers U, Bikker H, Denk G U, Rust C
Medizinische Klinik und Poliklinik II, LMU Klinikum der Universität München - Campus Großhadern, Marchioninistraße 15, 81377, München, Deutschland.
Internist (Berl). 2011 Oct;52(10):1234-7. doi: 10.1007/s00108-010-2775-2.
"Low phospholipid associated cholelithiasis" (LPAC) syndrome is an important differential diagnosis in younger patients with biliary symptoms after cholecystectomy and concomitant elevated serum liver tests. Typical symptoms include recurrence of biliary colics after cholecystectomy, echogenic material in the intrahepatic bile ducts, intrahepatic cholestasis of pregnancy or cholestasis under hormonal contraception and a family history of gallstone disease. Patients with LPAC syndrome can be successfully treated with ursodeoxycholic acid.
“低磷脂相关胆石症”（LPAC）综合征是胆囊切除术后出现胆道症状且血清肝功能检查结果同时升高的年轻患者的重要鉴别诊断。典型症状包括胆囊切除术后胆绞痛复发、肝内胆管出现回声物质、妊娠期肝内胆汁淤积或激素避孕下的胆汁淤积以及胆结石疾病家族史。LPAC综合征患者可用熊去氧胆酸成功治疗。
