• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Evolutionary twist on topoisomerases: conversion of gyrase to topoisomerase IV.拓扑异构酶的进化转变：促旋酶向拓扑异构酶IV的转变。
Proc Natl Acad Sci U S A. 2010 Dec 28;107(52):22363-4. doi: 10.1073/pnas.1016041108. Epub 2010 Dec 17.
2
A naturally chimeric type IIA topoisomerase in Aquifex aeolicus highlights an evolutionary path for the emergence of functional paralogs.水生栖热菌中天然嵌合的 IIA 拓扑异构酶突出了功能平行物出现的进化途径。
Proc Natl Acad Sci U S A. 2010 Dec 21;107(51):22055-9. doi: 10.1073/pnas.1012938107. Epub 2010 Nov 12.
3
What makes a type IIA topoisomerase a gyrase or a Topo IV?是什么使 IIA 型拓扑异构酶成为拓扑异构酶 IV 或回旋酶？
Nucleic Acids Res. 2021 Jun 21;49(11):6027-6042. doi: 10.1093/nar/gkab270.
4
The mechanism of negative DNA supercoiling: a cascade of DNA-induced conformational changes prepares gyrase for strand passage.负超螺旋DNA的机制：一系列由DNA诱导的构象变化为拓扑异构酶进行链穿入做好准备。
DNA Repair (Amst). 2014 Apr;16:23-34. doi: 10.1016/j.dnarep.2014.01.011. Epub 2014 Feb 22.
5
Novel symmetric and asymmetric DNA scission determinants for Streptococcus pneumoniae topoisomerase IV and gyrase are clustered at the DNA breakage site.肺炎链球菌拓扑异构酶IV和gyrase的新型对称和不对称DNA切割决定簇聚集在DNA断裂位点。
J Biol Chem. 2005 Apr 8;280(14):14252-63. doi: 10.1074/jbc.M500156200. Epub 2005 Jan 18.
6
In front of and behind the replication fork: bacterial type IIA topoisomerases.复制叉的前后：细菌 IIA 拓扑异构酶。
Cell Mol Life Sci. 2010 Jun;67(12):2001-24. doi: 10.1007/s00018-010-0299-5. Epub 2010 Feb 18.
7
Antibacterial activity of finafloxacin under different pH conditions against isogenic strains of Escherichia coli expressing combinations of defined mechanisms of fluoroquinolone resistance.不同 pH 条件下非那沙星对表达不同氟喹诺酮耐药机制组合的同源大肠埃希菌的抗菌活性。
J Antimicrob Chemother. 2010 Dec;65(12):2530-3. doi: 10.1093/jac/dkq375. Epub 2010 Oct 12.
8
Contribution of Type II Topoisomerase Mutations to Fluoroquinolone Resistance in Enterococcus faecium from Japanese Clinical Setting.日本临床环境中粪肠球菌II型拓扑异构酶突变对氟喹诺酮耐药性的贡献。
Microb Drug Resist. 2018 Jan/Feb;24(1):1-7. doi: 10.1089/mdr.2016.0328. Epub 2017 May 15.
9
Functional analysis of three topoisomerases that regulate DNA supercoiling levels in Chlamydia.对三种调节衣原体DNA超螺旋水平的拓扑异构酶的功能分析。
Mol Microbiol. 2016 Feb;99(3):484-96. doi: 10.1111/mmi.13241. Epub 2015 Nov 13.
10
Activities of gyrase and topoisomerase IV on positively supercoiled DNA.促旋酶和拓扑异构酶IV对正超螺旋DNA的活性。
Nucleic Acids Res. 2017 Sep 19;45(16):9611-9624. doi: 10.1093/nar/gkx649.

引用本文的文献

1
Two-Dimensional Gel Electrophoresis to Study the Activity of Type IIA Topoisomerases on Plasmid Replication Intermediates.二维凝胶电泳用于研究IIA型拓扑异构酶对质粒复制中间体的活性。
Biology (Basel). 2021 Nov 17;10(11):1195. doi: 10.3390/biology10111195.
2
DNA Topoisomerases.DNA拓扑异构酶
EcoSal Plus. 2015;6(2). doi: 10.1128/ecosalplus.ESP-0010-2014.

本文引用的文献

1
A naturally chimeric type IIA topoisomerase in Aquifex aeolicus highlights an evolutionary path for the emergence of functional paralogs.水生栖热菌中天然嵌合的 IIA 拓扑异构酶突出了功能平行物出现的进化途径。
Proc Natl Acad Sci U S A. 2010 Dec 21;107(51):22055-9. doi: 10.1073/pnas.1012938107. Epub 2010 Nov 12.
2
Escherichia coli condensin MukB stimulates topoisomerase IV activity by a direct physical interaction.大肠杆菌凝聚素 MukB 通过直接物理相互作用刺激拓扑异构酶 IV 活性。
Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):18832-7. doi: 10.1073/pnas.1008678107. Epub 2010 Oct 4.
3
Physical and functional interaction between the condensin MukB and the decatenase topoisomerase IV in Escherichia coli.在大肠杆菌中，凝聚素 MukB 与解旋酶拓扑异构酶 IV 之间的物理和功能相互作用。
Proc Natl Acad Sci U S A. 2010 Nov 2;107(44):18826-31. doi: 10.1073/pnas.1008140107. Epub 2010 Aug 9.
4
Mechanisms of chiral discrimination by topoisomerase IV.拓扑异构酶IV的手性识别机制。
Proc Natl Acad Sci U S A. 2009 Apr 28;106(17):6986-91. doi: 10.1073/pnas.0900574106. Epub 2009 Apr 9.
5
DNA topoisomerases: harnessing and constraining energy to govern chromosome topology.DNA拓扑异构酶：利用和控制能量以调控染色体拓扑结构
Q Rev Biophys. 2008 Feb;41(1):41-101. doi: 10.1017/S003358350800468X.
6
Origin and evolution of DNA topoisomerases.DNA拓扑异构酶的起源与进化
Biochimie. 2007 Apr;89(4):427-46. doi: 10.1016/j.biochi.2006.12.009. Epub 2007 Jan 4.
7
The "GyrA-box" is required for the ability of DNA gyrase to wrap DNA and catalyze the supercoiling reaction.“GyrA框”是DNA促旋酶包裹DNA并催化超螺旋反应能力所必需的。
J Biol Chem. 2006 Feb 10;281(6):3738-42. doi: 10.1074/jbc.M511160200. Epub 2005 Dec 5.
8
Human topoisomerase IIalpha rapidly relaxes positively supercoiled DNA: implications for enzyme action ahead of replication forks.人类拓扑异构酶IIα能快速松弛正超螺旋DNA：对复制叉前酶作用的启示。
J Biol Chem. 2005 Nov 25;280(47):39337-45. doi: 10.1074/jbc.M503320200. Epub 2005 Sep 27.
9
The structural basis for substrate specificity in DNA topoisomerase IV.DNA拓扑异构酶IV中底物特异性的结构基础。
J Mol Biol. 2005 Aug 19;351(3):545-61. doi: 10.1016/j.jmb.2005.06.029.
10
Single-molecule study of DNA unlinking by eukaryotic and prokaryotic type-II topoisomerases.真核生物和原核生物II型拓扑异构酶解开DNA链的单分子研究。
Proc Natl Acad Sci U S A. 2003 Aug 19;100(17):9820-5. doi: 10.1073/pnas.1631550100. Epub 2003 Aug 5.

Evolutionary twist on topoisomerases: conversion of gyrase to topoisomerase IV.

作者信息

Neuman Keir C

机构信息

Laboratory of Molecular Biophysics, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892, USA.

出版信息

Proc Natl Acad Sci U S A. 2010 Dec 28;107(52):22363-4. doi: 10.1073/pnas.1016041108. Epub 2010 Dec 17.

DOI:10.1073/pnas.1016041108
PMID:21169503
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3012485/
Abstract
摘要