Crompton G K
Respiratory Medicine Service, Northern, General Hospital, Edinburgh, United Kingdom.
Lung. 1990;168 Suppl:658-62. doi: 10.1007/BF02718191.
Fifty percent or less of adult patients can be expected to be able to use the conventional metered dose inhaler (MDI) efficiently if the only tuition they receive is the manufacturer's instruction pamphlet and a high proportion of patients should be expected to develop a poor inhalation technique unless their ability to use an MDI is checked regularly. Because of these problems I believe that the future of the conventional MDI is limited. The new generation of inhalation devices have exciting design features and are undoubtedly better than established inhalation systems in that they are as effective and much easier to use. When these new devices are all available for the delivery of bronchodilators and corticosteroids there is no doubt that many patients will benefit. They should be prescribed in preference to the MDI for all patients whose ability to use a conventional pressurized inhaler is not routinely assessed prior to the institution of therapy and at regular intervals thereafter.
如果成年患者仅接受制造商的使用说明手册作为指导，预计只有50%或更少的患者能够有效使用传统定量吸入器（MDI），并且除非定期检查他们使用MDI的能力，否则预计会有很大比例的患者养成不良的吸入技术。由于这些问题，我认为传统MDI的前景有限。新一代吸入装置具有令人兴奋的设计特点，无疑比现有的吸入系统更好，因为它们同样有效且使用起来容易得多。当所有这些新装置都可用于递送支气管扩张剂和皮质类固醇时，毫无疑问许多患者将从中受益。对于所有在开始治疗前未常规评估其使用传统压力定量吸入器能力且此后未定期评估的患者，应优先开具这些新装置而非MDI。
