Department of Paediatrics, Lady Hardinge Medical College and assoc Kalawati Saran Children's Hospital, Bangla Sahib Marg, N Delhi 110001, India.
Paediatr Respir Rev. 2011 Mar;12(1):52-9. doi: 10.1016/j.prrv.2010.09.011. Epub 2010 Oct 16.
Childhood pneumonias are an important cause of morbidity and mortality and annually contribute to over 2 million deaths among children under five years of age. To combat this, a standardized case management protocol developed by the World Health Organization has been adopted by the National programs in most high burden, resource constrained settings. This can detect patients with pneumonia early on and with ease at community level and also identify those who are at risk of dying due to a severe form of the disease if not referred or appropriately treated. However, as most deaths due to pneumonia occur in health facilities, it is equally important to standardise treatment at a facility level with pulse oximetry, regular monitoring for complications and the judicious use of antibiotics. The challenge is to identify other respiratory illnesses which mimic pneumonia resulting in under treatment with bronchodilators and over usage of antibiotics. This becomes particularly important in developing countries which have the dual burden of both the infectious and non-infectious illnesses. The strategy also needs refinement for diagnosing and treating pneumonia in severely under nourished and / or HIV co-infected children who are both at higher risk of disease as well as death due to it.
儿童肺炎是发病率和死亡率的一个重要原因,每年导致 5 岁以下儿童死亡超过 200 万例。为了应对这一问题,世界卫生组织制定了标准化的病例管理方案,已被大多数高负担、资源有限的国家纳入国家规划。该方案可以在社区层面及早轻松地发现肺炎患者,并识别出那些因严重疾病而有死亡风险的患者,如果不进行转诊或适当治疗。然而,由于大多数肺炎死亡发生在医疗机构,因此同样重要的是在医疗机构层面使用脉搏血氧仪进行标准化治疗,定期监测并发症,并合理使用抗生素。挑战在于识别出其他类似肺炎的呼吸疾病,这些疾病会导致支气管扩张剂治疗不足和抗生素过度使用。在同时存在传染性和非传染性疾病双重负担的发展中国家,这一点尤为重要。对于因严重营养不良和/或合并感染艾滋病毒而处于更高疾病和死亡风险的儿童,该策略也需要进行精细化,以诊断和治疗肺炎。