Division of Infectious Diseases, Medicine, Johns Hopkins University, Baltimore, MD, USA.
Sex Transm Dis. 2011 Feb;38(2):74-8. doi: 10.1097/OLQ.0b013e3182039d7f.
To determine whether women who collect self-collected vaginal swabs at home demonstrated a higher positivity of Chlamydia trachomatis than women in family planning clinics.
Collection kits for vaginal swabs were internet requested, collected at home, and mailed to a laboratory for testing; questionnaires were completed about acceptability and sexual risk history. Infected women received treatment at participating clinics. Age-specific prevalences were compared to those from family planning clinics.
Chlamydia positivity was 10.3% for 1171 females mailing swabs; prevalences ranged from 3.3% to 5.5% in family planning. Positivity for internet age groups was much higher than those for family planning age groups. The positivity for internet participants ranged from a low of 4.4% in Baltimore in 2005 to a high of 15.2% Baltimore in 2007. Family planning clinic prevalence in Baltimore and Maryland ranged from a low of 3.3% in Baltimore in 2006 to a high of 5.5% in Baltimore in 2008. The median age for all years for internet users in Baltimore and Maryland combined was 23 years; the median age for all years for attendees to family planning clinics who had chlamydia testing performed was 23 years.
Internet recruited women demonstrated higher positivity of chlamydia than those in family planning, providing new options for chlamydia screening programs.
确定在家中自行采集阴道拭子的女性与计划生育诊所中的女性相比，沙眼衣原体（Chlamydia trachomatis）的阳性率是否更高。
通过互联网申请阴道拭子采集套件，在家中采集样本，并邮寄至实验室进行检测；完成关于可接受性和性风险史的问卷。感染的女性在参与的诊所接受治疗。比较了年龄特异性的患病率与计划生育诊所的患病率。
1171 名邮寄拭子的女性中沙眼衣原体阳性率为 10.3%；计划生育中患病率范围为 3.3%至 5.5%。互联网年龄组的阳性率明显高于计划生育年龄组。互联网参与者的阳性率从 2005 年巴尔的摩的 4.4%到 2007 年巴尔的摩的 15.2%不等。巴尔的摩和马里兰州计划生育诊所的患病率从 2006 年巴尔的摩的 3.3%到 2008 年巴尔的摩的 5.5%不等。巴尔的摩和马里兰州所有年份的互联网用户的中位数年龄为 23 岁；所有年份进行衣原体检测的计划生育诊所就诊者的中位数年龄为 23 岁。
互联网招募的女性沙眼衣原体阳性率高于计划生育，为衣原体筛查项目提供了新的选择。
