从射干中分离得到的具有显著杀软体动物活性的新二聚体环阿尔廷三萜。

A new dimeric iridal triterpenoid from Belamcanda chinensis with significant molluscicide activity.

机构信息

Key Laboratory of Mountain Ecological Restoration and Bioresource Utilization, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, PR China.

出版信息

Org Lett. 2011 Feb 4;13(3):462-5. doi: 10.1021/ol102796k. Epub 2010 Dec 21.

DOI:10.1021/ol102796k

PMID:21174449

Abstract

An unprecedented dimeric triterpenoid, designated dibelamcandal A, with a six-membered ring linking two iridal type triterpenoid nuclei, was isolated from the rhizome of Belamcanda chinensis. Its structure was determined by extensive spectroscopic measurements, including IR, ESI-MS, HR-ESI-MS, and 1D and 2D NMR. It demonstrated significant molluscicide activity against Pomacea canaliculata.

摘要

从国产射干Belamcanda chinensis 的根茎中分离得到了一种前所未有的二聚型三萜类化合物，命名为 dibelamcandal A，它由一个六元环连接两个伊里德型三萜核组成。通过广泛的光谱测量，包括 IR、ESI-MS、HR-ESI-MS 以及 1D 和 2D NMR，确定了其结构。该化合物对福寿螺Pomacea canaliculata 具有显著的杀螺活性。