Venkata Vani, Irulandy Ponniah
Department of Oral And Maxillofacial Pathology, Tamil Nadu Government Dental College And Hospital, Chennai, India.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011 Jan;111(1):e32-9. doi: 10.1016/j.tripleo.2010.08.019.
Data are not available regarding distribution of minor salivary gland tumors from the specialist pathology setting in India. The purpose of this study was to determine the relative frequency and distribution of minor salivary gland tumors and to compare the data with pertinent studies.
The records and archival samples of the Department of Oral and Maxillofacial Pathology, Tamil Nadu Government Dental College and Hospital, Chennai, India, served as source material for this retrospective study. All cases with a diagnosis of minor salivary gland tumors recorded between 1971 and August 2008 were retrieved and reviewed.
A total of 185 minor salivary gland tumors were identified with reference to the latest World Health Organization classification, representing a relative frequency of 1.52% over the study period of 37 years (1971-2008) from 12,147 biopsy samples. Malignant tumors (75%) predominated over benign tumors (25%). The age range was 12-82 years with a mean of 46 years. Mucoepidermoid carcinoma was the most frequent tumor (34%), followed by pleomorphic adenoma (22%), adenoid cystic carcinoma (15%), and polymorphous low-grade adenocarcinoma (10%). The overall gender distribution was almost equal. Palate was the most frequent involved site, followed by alveolar mucosa and floor of the mouth.
The present study shows a higher proportion of malignant tumors and a tendency toward male predilection during the past decades. The overall data are consistent with hospital-based studies from Asia and series from other geographic regions.
关于印度专科病理学背景下小涎腺肿瘤的分布情况，尚无相关数据。本研究的目的是确定小涎腺肿瘤的相对频率和分布，并将数据与相关研究进行比较。
印度钦奈泰米尔纳德邦政府牙科学院及医院口腔颌面病理学系的记录和存档样本用作本回顾性研究的源材料。检索并回顾了1971年至2008年8月期间所有诊断为小涎腺肿瘤的病例。
根据世界卫生组织的最新分类，共鉴定出185例小涎腺肿瘤，在1971年至2008年这37年的研究期间，从12147份活检样本中所占相对频率为1.52%。恶性肿瘤（75%）多于良性肿瘤（25%）。年龄范围为12至82岁，平均年龄为46岁。黏液表皮样癌是最常见的肿瘤（34%），其次是多形性腺瘤（22%）、腺样囊性癌（15%）和多形性低度腺癌（10%）。总体性别分布几乎相等。腭部是最常受累的部位，其次是牙槽黏膜和口底。
本研究显示在过去几十年中恶性肿瘤比例较高，且有男性偏好的趋势。总体数据与来自亚洲的基于医院的研究以及其他地理区域的系列研究一致。
