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蒙若林霍河(巴西)原污水排放后水体的遗传毒性和致突变性。

Genotoxicity and mutagenicity of water samples from the Monjolinho River (Brazil) after receiving untreated effluents.

机构信息

Department of Biology, Institute of Biosciences, São Paulo State University (UNESP), Av. 24A, 1515, Bela Vista, Rio Claro, São Paulo, CEP 13506-900, Brazil.

出版信息

Ecotoxicol Environ Saf. 2011 May;74(4):826-33. doi: 10.1016/j.ecoenv.2010.11.006. Epub 2010 Dec 21.

DOI:10.1016/j.ecoenv.2010.11.006
PMID:21176964
Abstract

Cytotoxicity, genotoxicity and mutagenicity assays, using the Allium cepa test-system, were carried out in order to evaluate the effects of domestic and industrial effluents in the Monjolinho River in different seasons of the year. In the summer and intermediate seasons, chromosome aberration, micronuclei, cell death and inhibition of the mitotic index were observed in water samples collected at different sites. In the winter, either chromosome or cellular alterations were not observed. Through chemical analysis, we infer that the excessive metals such as Pb, Ni and Cu were mainly responsible for the effects observed in A. cepa cells. Limnologic analysis like electrical conductivity, dissolved oxygen and the presence of nitrogen and phosphated compounds showed that the river's contamination is due to organic matter discharge along its course. Moreover we note that this river had a higher self-depurative capacity at the end of its course, before its confluence with the Jacaré-Guaçu River.

摘要

为了评估不同季节蒙若林霍河(Monjolinho River)中城市和工业废水的影响,利用洋葱根尖细胞染色体畸变试验(Allium cepa test-system),对其进行了细胞毒性、遗传毒性和致突变性检测。在夏季和仲夏季,在不同地点采集水样,观察到了染色体畸变、微核、细胞死亡和有丝分裂指数抑制。在冬季,没有观察到染色体或细胞变化。通过化学分析,我们推断,过多的金属,如 Pb、Ni 和 Cu,是导致洋葱根尖细胞出现这些变化的主要原因。像电导率、溶解氧以及氮磷化合物的存在等湖沼学分析表明,这条河的污染是由于其沿途排放的有机物造成的。此外,我们注意到,在与雅卡雷瓜苏河(Jacaré-Guaçu River)汇流之前,这条河在其下游具有更高的自净化能力。

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