Suppr超能文献

英国出生队列中人格解体综合征的患病率及其儿童期前因。

Prevalence and childhood antecedents of depersonalization syndrome in a UK birth cohort.

机构信息

King's College London, Psychological Medicine, Institute of Psychiatry, Weston Education Centre, London, SE5 9RJ, UK.

出版信息

Soc Psychiatry Psychiatr Epidemiol. 2012 Feb;47(2):253-61. doi: 10.1007/s00127-010-0327-7. Epub 2010 Dec 23.

Abstract

PURPOSE

Depersonalization syndrome is characterised by a sense of unreality about the self [depersonalization (DP)] and/or the outside world [derealization (DR)]. Prevalence estimates vary widely. Little is known about childhood antecedents of the disorder although emotional abuse is thought to play a role.

METHODS

Longitudinal data from 3,275 participants of a UK population-based birth cohort (the MRC National Survey of Health and Development) were used to: (1) assess the prevalence of DP syndrome at age 36, measured by the Present State Examination (PSE); and (2) examine the effects of a range of socio-demographic, childhood adversity and emotional responses as potential risk factors for DP.

RESULTS

Thirty three survey members were classified with DP, yielding a prevalence of 0.95% [95% confidence intervals (CI) 0.56-1.34]. There were no associations with socio-economic status, parental death or divorce; self-reported accidents, childhood depression, tendency to daydream or reactions to criticism. However, teacher-estimated childhood anxiety was a strong independent predictor of adult depersonalization, and there were strong cross-sectional relationships between DP and anxiety and depression caseness.

CONCLUSIONS

To our knowledge this is the first study assessing nationwide prevalence of the DP syndrome and uses longitudinal data to explore childhood risk factors for adult DP. The prevalence of adult DP was slightly lower than reported by other surveys. The study found that childhood anxiety was the only significant predictor of the adult DP syndrome, supporting the view that depersonalisation disorder forms part of the spectrum of responses to anxiety.

摘要

目的

人格解体综合征的特征是自我[人格解体 (DP)]和/或外部世界[现实解体 (DR)]的不真实感。患病率估计差异很大。尽管人们认为情感虐待起了作用,但对该疾病的童年前因知之甚少。

方法

使用英国人群出生队列(MRC 国家健康与发展调查)3275 名参与者的纵向数据:(1) 通过现状检查 (PSE) 评估 36 岁时 DP 综合征的患病率;(2) 研究一系列社会人口学、儿童逆境和情绪反应作为 DP 的潜在危险因素的影响。

结果

33 名调查参与者被归类为 DP,患病率为 0.95%[95%置信区间 (CI) 0.56-1.34]。与社会经济地位、父母死亡或离婚、自我报告的事故、儿童期抑郁症、白日梦倾向或对批评的反应无关。然而,教师评估的儿童焦虑是成年人格解体的一个强烈独立预测因素,DP 与焦虑和抑郁病例之间存在强烈的横断面关系。

结论

据我们所知,这是第一项评估 DP 综合征全国患病率的研究,并使用纵向数据探讨了儿童时期成年 DP 的危险因素。成年 DP 的患病率略低于其他调查的报告。该研究发现,儿童时期的焦虑是成年 DP 综合征的唯一显著预测因素,这支持了人格解体障碍是焦虑反应谱的一部分的观点。

相似文献

1
Prevalence and childhood antecedents of depersonalization syndrome in a UK birth cohort.
Soc Psychiatry Psychiatr Epidemiol. 2012 Feb;47(2):253-61. doi: 10.1007/s00127-010-0327-7. Epub 2010 Dec 23.
2
The experimental induction of depersonalization and derealization in panic disorder and nonanxious subjects.
Behav Res Ther. 1994 Jun;32(5):511-9. doi: 10.1016/0005-7967(94)90138-4.
4
[Depersonalisation/derealization - clinical picture, diagnostics and therapy].
Z Psychosom Med Psychother. 2009;55(2):113-40. doi: 10.13109/zptm.2009.55.2.113.
5
Prevalence, correlates, and predictors of depersonalization experiences in the German general population.
J Nerv Ment Dis. 2009 Jul;197(7):499-506. doi: 10.1097/NMD.0b013e3181aacd94.
8
Prevalence and correlates of depersonalization in students aged 12-18 years in Germany.
Soc Psychiatry Psychiatr Epidemiol. 2015 Jun;50(6):995-1003. doi: 10.1007/s00127-014-0957-2. Epub 2014 Sep 9.

引用本文的文献

1
Clinical characteristics of 217 Chinese cases with depersonalization/derealization disorder.
BMC Psychiatry. 2024 Sep 4;24(1):597. doi: 10.1186/s12888-024-06028-z.
2
Confrontation with others' emotions changes bodily resonance differently in those with low and high levels of depersonalization.
Philos Trans R Soc Lond B Biol Sci. 2024 Aug 26;379(1908):20230248. doi: 10.1098/rstb.2023.0248. Epub 2024 Jul 15.
3
Explicit and implicit sense of agency in depersonalisation experiences.
Sci Rep. 2024 Jul 4;14(1):15396. doi: 10.1038/s41598-024-65862-z.
4
Review of Major Social Determinants of Health in Schizophrenia-Spectrum Disorders: II. Assessments.
Schizophr Bull. 2023 Jul 4;49(4):851-866. doi: 10.1093/schbul/sbad024.
5
Depersonalization disorder as a systematic downregulation of interoceptive signals.
Sci Rep. 2022 Dec 21;12(1):22123. doi: 10.1038/s41598-022-22277-y.
6
Potential Targets for Noninvasive Brain Stimulation on Depersonalization-Derealization Disorder.
Brain Sci. 2022 Aug 21;12(8):1112. doi: 10.3390/brainsci12081112.
7
Zoomed out: digital media use and depersonalization experiences during the COVID-19 lockdown.
Sci Rep. 2022 Mar 10;12(1):3888. doi: 10.1038/s41598-022-07657-8.
8
Dissociative Symptoms in Bipolar Disorder: Impact on Clinical Course and Treatment Response.
Front Psychiatry. 2021 Oct 25;12:732843. doi: 10.3389/fpsyt.2021.732843. eCollection 2021.
9
Traumatic Events, Social Adversity and Discrimination as Risk Factors for Psychosis - An Umbrella Review.
Front Psychiatry. 2021 Oct 22;12:665957. doi: 10.3389/fpsyt.2021.665957. eCollection 2021.
10
Traumatic experiences in childhood and adolescence: a meta-analysis of prospective studies assessing risk for psychosis.
Eur Child Adolesc Psychiatry. 2022 Feb;31(2):215-228. doi: 10.1007/s00787-020-01574-9. Epub 2020 Jun 24.

本文引用的文献

1
Prevalence, correlates, and predictors of depersonalization experiences in the German general population.
J Nerv Ment Dis. 2009 Jul;197(7):499-506. doi: 10.1097/NMD.0b013e3181aacd94.
2
Is depersonalization disorder initiated by illicit drug use any different? A survey of 394 adults.
J Clin Psychiatry. 2009 Oct;70(10):1358-64. doi: 10.4088/JCP.08m04370. Epub 2009 Jun 16.
3
Depersonalization and individualism: the effect of culture on symptom profiles in panic disorder.
J Nerv Ment Dis. 2007 Dec;195(12):989-95. doi: 10.1097/NMD.0b013e31815c19f7.
4
Depersonalization, mindfulness, and childhood trauma.
J Nerv Ment Dis. 2007 Aug;195(8):693-6. doi: 10.1097/NMD.0b013e31811f4492.
5
Depersonalization in psychiatric patients: a transcultural study.
J Nerv Ment Dis. 2006 May;194(5):356-61. doi: 10.1097/01.nmd.0000218071.32072.74.
6
The protective role of trait anxiety: a longitudinal cohort study.
Psychol Med. 2006 Mar;36(3):345-51. doi: 10.1017/S0033291705006847. Epub 2006 Jan 5.
7
Dissociative disorders among adults in the community, impaired functioning, and axis I and II comorbidity.
J Psychiatr Res. 2006 Mar;40(2):131-40. doi: 10.1016/j.jpsychires.2005.03.003. Epub 2005 Dec 6.
8
Cohort Profile: The 1946 National Birth Cohort (MRC National Survey of Health and Development).
Int J Epidemiol. 2006 Feb;35(1):49-54. doi: 10.1093/ije/dyi201. Epub 2005 Oct 4.
10
The epidemiology of depersonalisation and derealisation. A systematic review.
Soc Psychiatry Psychiatr Epidemiol. 2004 Jan;39(1):9-18. doi: 10.1007/s00127-004-0701-4.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验