Department of Anaesthesia, St. George's Hospital, London, UK.
Int J Obstet Anesth. 2011 Apr;20(2):181-4. doi: 10.1016/j.ijoa.2010.10.006. Epub 2010 Dec 22.
Brugada syndrome is a common cause of sudden cardiac death. We report the anaesthetic management of a woman with Brugada syndrome for elective caesarean section of twins. There are few reports of this disease in pregnancy and we believe this is the first of elective caesarean section in a parturient with the syndrome. The characteristic electrocardiographic changes of the syndrome are linked to sodium channel blockers including local anaesthetics such as bupivacaine. The use of bupivacaine for intrathecal central neuraxial blockade as well as other drugs commonly used in obstetric anaesthesia is discussed.
Brugada 综合征是心源性猝死的常见原因。我们报告了一例 Brugada 综合征女性行择期双胞胎剖宫产的麻醉管理。该疾病在妊娠中很少见，我们认为这是首例综合征产妇行择期剖宫产。该综合征的特征性心电图改变与包括布比卡因等局部麻醉剂在内的钠通道阻滞剂有关。讨论了布比卡因用于鞘内中枢神经轴阻滞以及产科麻醉中常用的其他药物的使用。
