Mayes Taryn L, Bernstein Ira H, Haley Charlotte L, Kennard Betsy D, Emslie Graham J
Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390-8589, USA.
J Child Adolesc Psychopharmacol. 2010 Dec;20(6):513-6. doi: 10.1089/cap.2010.0063.
The aim of this study was to present the reliability and validity of the Children's Depression Rating Scale-Revised (CDRS-R) in the adolescent age group.
Adolescents with symptoms of depression were assessed using the CDRS-R and global severity and functioning scales at screening, baseline, and after 12 weeks of fluoxetine treatment. Global improvement was also assessed at week 12 (or exit). Reliability and validity were analyzed using Classical Test Theory (item-total correlations and internal consistency) and correlations between the CDRS-R and other outcomes.
Adolescents (n = 145) were evaluated at screening; 113 (77.9%) met criteria for major depressive disorder, 8 (5.5%) had subthreshold depressive symptoms, and 24 (16.6%) had minimal depressive symptoms. Ninety-four adolescents had a baseline visit after 1 week, and 88 were treated with fluoxetine. Internal consistency for the CDRS-R was good at all three visits (screening: 0.79; baseline: 0.74; exit: 0.92), and total score was highly correlated with global severity (r = 0.87, 0.80, and 0.93; p < 0.01). Only exit CDRS-R score was significantly correlated with global functioning (Children's Global Assessment Scale; r = -0.77; p < 0.01). Reductions on the CDRS-R total score were highly correlated with improvement scores at exit (Clinical Global Impressions-Improvement; r = -0.83; p < 0.01).
The results demonstrate good reliability and validity in adolescents with depression.
本研究旨在呈现儿童抑郁评定量表修订版(CDRS-R)在青少年年龄组中的信度和效度。
对有抑郁症状的青少年在筛查、基线期以及氟西汀治疗12周后使用CDRS-R以及整体严重程度和功能量表进行评估。在第12周(或结束时)也评估了整体改善情况。使用经典测试理论(项目总分相关性和内部一致性)以及CDRS-R与其他结果之间的相关性来分析信度和效度。
在筛查时对145名青少年进行了评估;113名(77.9%)符合重度抑郁症标准,8名(5.5%)有阈下抑郁症状,24名(16.6%)有轻微抑郁症状。94名青少年在1周后进行了基线访视,88名接受了氟西汀治疗。CDRS-R在所有三次访视中的内部一致性都良好(筛查:0.79;基线:0.74;结束时:0.92),总分与整体严重程度高度相关(r = 0.87、0.80和0.93;p < 0.01)。只有结束时的CDRS-R分数与整体功能显著相关(儿童整体评估量表;r = -0.77;p < 0.01)。CDRS-R总分的降低与结束时的改善分数高度相关(临床总体印象-改善;r = -0.83;p < 0.01)。
结果表明CDRS-R在患有抑郁症的青少年中具有良好的信度和效度。