Izawa Takeshi, Murai Fumi, Akiyoshi Hideo, Ohashi Fumihito, Yamate Jyoji, Kuwamura Mitsuru
Laboratory of Veterinary Pathology, Osaka Prefecture University, Rinku-Orai Kita, Izumisano, Osaka, Japan.
J Vet Med Sci. 2011 May;73(5):697-700. doi: 10.1292/jvms.10-0503. Epub 2010 Dec 24.
A 6-month-old male miniature pinscher dog developed chronic ascites, formation of fibrous membrane covering the abdominal organs, and numerous adhesions between the intestinal loops. The membrane and adhesions were surgically removed twice, but the dog died 1 month after initial presentation. Necropsy revealed recurrence of the membrane and intestinal adhesions. The fibrous membrane was composed of a thick layer of mature collagenous connective tissue, covered by immature collagenous connective tissue with mild lymphoplasmacytic infiltration, prominent neovascularization, and fibrin exudation. Similar fibrotic lesions were observed in the serosa of the liver, spleen, stomach and intestines. These findings are consistent with encapsulating peritoneal fibrosis reported in humans and dogs. The dog also had a maldeveloped liver, which is characterized by disorganized hepatic lobules and disarranged hepatic cords.
一只6个月大的雄性迷你杜宾犬出现慢性腹水、覆盖腹部器官的纤维膜形成以及肠袢之间大量粘连。该膜和粘连组织曾两次通过手术切除，但这只狗在初次就诊后1个月死亡。尸检发现膜和肠粘连复发。纤维膜由一层厚厚的成熟胶原结缔组织组成，表面覆盖着不成熟的胶原结缔组织，伴有轻度淋巴浆细胞浸润、明显的新生血管形成和纤维蛋白渗出。在肝脏、脾脏、胃和肠道的浆膜中也观察到类似的纤维化病变。这些发现与人类和犬类中报道的包裹性腹膜纤维化一致。这只狗还存在肝脏发育不良，其特征为肝小叶结构紊乱和肝索排列紊乱。
