Valderrabano Victor, Steiger Christina
Orthopaedic Department, University of Basel, Spitalstr. 21, 4031 Basel, Switzerland.
J Aging Res. 2010 Dec 6;2011:374653. doi: 10.4061/2011/374653.
Osteoarthritis (OA) is a degenerative joint disease with a high prevalence among older people. To date, the pathogenesis of the disease and the link between muscle function and OA is not entirely understood. As there is no known cure for OA, current research focuses on prevention and symptomatic treatment of the disorder. Recent research has indicated that muscle weakness precedes the onset of OA symptoms. Furthermore, several studies show a beneficial effect of land-based aerobic and strengthening exercises on pain relief and joint function. Therefore, current research focuses on the possibility to employ exercise and sports in the prevention and treatment of OA.
骨关节炎（OA）是一种在老年人中患病率很高的退行性关节疾病。迄今为止，该疾病的发病机制以及肌肉功能与骨关节炎之间的联系尚未完全明确。由于目前尚无已知的骨关节炎治愈方法，当前的研究重点在于该疾病的预防和对症治疗。最近的研究表明，肌肉无力先于骨关节炎症状出现。此外，多项研究显示陆上有氧运动和力量训练对缓解疼痛及改善关节功能具有有益作用。因此，当前的研究聚焦于运用运动和体育活动来预防和治疗骨关节炎的可能性。
