用于疾病探索和药物筛选的细胞模型。
Cellular models for disease exploring and drug screening.
机构信息
State Key Laboratory of Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.
Graduate School, Chinese Academy of Sciences, Beijing, 100049, China.
出版信息
Protein Cell. 2010 Apr;1(4):355-362. doi: 10.1007/s13238-010-0027-9. Epub 2010 May 8.
Abstract
The biopharmaceutical industry has been greatly promoted by the application of drug and disease models, including both animal and cellular models. In particular, the emergence of induced pluripotent stem cells (iPSC) makes it possible to create a large number of disease-specific cells in vitro. This review introduces the most widely applied models and their specialties.
摘要
生物医药产业在药物和疾病模型的应用推动下得到了极大的发展，包括动物模型和细胞模型。特别是诱导多能干细胞（iPSC）的出现，使得在体外大量创建特定疾病的细胞成为可能。本文介绍了最广泛应用的模型及其特点。
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