Zain R B, Fei Y J
Department of Oral Pathology and Oral Medicine, Dental Faculty, University of Malaya, Kuala Lumpur.
Oral Surg Oral Med Oral Pathol. 1990 Oct;70(4):466-70. doi: 10.1016/0030-4220(90)90212-b.
Two hundred four cases of fibrous lesions of the gingiva were studied histologically for the presence of calcified tissue, the nature of the connective tissue, the type of keratinization, and the degree of epithelial thickness. Initially these lesions were subcategorized into four specific entities, namely fibrous epulis, fibroepithelial polyp, calcifying fibroblastic granuloma, and ossifying fibrous epulis. It was found that 46.5% of the lesions contained calcifications. The connective tissue was represented predominantly by either the collagenous type (50.5%) or the mixed (cellular and collagenous) type (44.6%). It was also found that 36% of the lesions were ulcerated, and, of these, 79.5% were associated with the cellular type of connective tissue and calcifications. In an attempt to subcategorize the fibrous lesions into specific entities, it was found that 32 cases (15.7%) had mixed features. This fact supports the suggestion that these lesions are stages in the spectrum of a single disease process and should collectively be termed fibroblastic gingival lesions. However, it is also suggested that the two terms, namely peripheral fibroma and fibrous epulis with and without ossification, should be retained whereas the usage of other terminologies should be avoided.
对204例牙龈纤维性病变进行了组织学研究，以确定钙化组织的存在、结缔组织的性质、角化类型以及上皮厚度。最初，这些病变被细分为四个特定类型，即纤维性龈瘤、纤维上皮性息肉、钙化性成纤维细胞肉芽肿和骨化性纤维性龈瘤。结果发现，46.5%的病变含有钙化。结缔组织主要由胶原类型（50.5%）或混合（细胞性和胶原性）类型（44.6%）构成。还发现36%的病变有溃疡形成，其中79.5%与细胞性结缔组织类型和钙化有关。为了将纤维性病变细分为特定类型，发现有32例（15.7%）具有混合特征。这一事实支持了以下观点，即这些病变是单一疾病过程谱中的不同阶段，应统称为成纤维细胞性牙龈病变。然而，也有人建议应保留“外周性纤维瘤”和“有或无骨化的纤维性龈瘤”这两个术语，而应避免使用其他术语。
