Department of Obstetrics and Gynecology, National Taiwan University Hospital, Taipei, Taiwan.
Fertil Steril. 2011 May;95(6):2134-6, 2136.e1. doi: 10.1016/j.fertnstert.2010.12.007. Epub 2011 Jan 5.
Abdominal mesotherapy injection of recombinant human FSH (rhFSH) was well tolerated with increased net absorption (AUC0-∞ 4,655.3 IU·h/L and t1/2 247.6 h) up to 360 hours compared with those of 120 hours (AUC0-∞ 1,915.7 IU·h/L and t1/2 101.8 h). The extended absorption of rhFSH suggests that abdominal mesotherapy injection mode be considered for future administration of rhFSH in controlled ovarian hyperstimulation.
与 120 小时（AUC0-∞ 1,915.7 IU·h/L 和 t1/2 101.8 h）相比，重组人卵泡刺激素（rhFSH）的腹部间质注射具有更好的耐受性，其净吸收增加（AUC0-∞ 4,655.3 IU·h/L 和 t1/2 247.6 h），最长可达 360 小时。rhFSH 的延长吸收表明，腹部间质注射方式可考虑用于未来的控制性卵巢过度刺激中 rhFSH 的给药。
