Love Emma J, Murrell J, Whay H R
Department of Clinical Veterinary Science, University of Bristol, Langford, UK.
Vet Anaesth Analg. 2011 Jan;38(1):3-14. doi: 10.1111/j.1467-2995.2010.00580.x.
This review evaluates the thermal and mechanical nociceptive threshold testing techniques that have been used in horses and discusses them with reference to their applications, limitations and the factors which can influence both the testing procedure itself and the animal's responses. Methods to optimise the reliability and repeatability of the testing procedures are suggested and the potential clinical applications discussed.
Web of Science and Medline.
Thermal and mechanical nociceptive threshold testing techniques have valuable roles in both the identification of altered nociceptive function and the pre-clinical evaluation of analgesics in horses.
本综述评估了已用于马匹的热痛觉和机械痛觉阈值测试技术,并参照其应用、局限性以及可能影响测试过程本身和动物反应的因素进行了讨论。文中提出了优化测试程序可靠性和可重复性的方法,并探讨了其潜在的临床应用。
科学网和医学期刊数据库。
热痛觉和机械痛觉阈值测试技术在识别马匹痛觉功能改变以及镇痛药临床前评估中均具有重要作用。