人博卡病毒是一种危及生命的感染的原因。
Human bocavirus as the cause of a life-threatening infection.
机构信息
Institute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Slovenia.
出版信息
J Clin Microbiol. 2011 Mar;49(3):1179-81. doi: 10.1128/JCM.02362-10. Epub 2011 Jan 12.
Abstract
Human bocavirus is a recently described respiratory pathogen. A case of a life-threatening human bocavirus infection of a previously healthy pediatric patient is described. An initial clinical presentation of acute bronchiolitis developed into an extremely severe course of disease characterized by pneumothorax, pneumomediastinum, and acute respiratory failure with pronounced air-leak syndrome.
摘要
人博卡病毒是人呼吸道病原体。描述了一例先前健康的儿科患者发生危及生命的人博卡病毒感染的病例。最初的临床表现为急性细支气管炎，发展为极其严重的疾病过程，特征为气胸、纵隔气肿和伴有明显空气泄漏综合征的急性呼吸衰竭。
相似文献
1
Human bocavirus as the cause of a life-threatening infection.人博卡病毒是一种危及生命的感染的原因。
J Clin Microbiol. 2011 Mar;49(3):1179-81. doi: 10.1128/JCM.02362-10. Epub 2011 Jan 12.
2
Life-threatening respiratory tract disease with human bocavirus-1 infection in a 4-year-old child.4 岁儿童因感染人博卡病毒 1 型而患上危及生命的呼吸道疾病。
J Clin Microbiol. 2012 Feb;50(2):531-2. doi: 10.1128/JCM.05706-11. Epub 2011 Nov 30.
3
[Very rare and life-threatening complications of bocavirus bronchiolitis: pneumomediastinum and bilateral pneumothorax].博卡病毒细支气管炎的极其罕见且危及生命的并发症：纵隔气肿和双侧气胸
Mikrobiyol Bul. 2016 Jan;50(1):159-64. doi: 10.5578/mb.10312.
4
Fatal subacute myocarditis associated with human bocavirus 2 in a 13-month-old child.一名13个月大儿童患与人类博卡病毒2型相关的致命性亚急性心肌炎。
J Clin Microbiol. 2014 Mar;52(3):1006-8. doi: 10.1128/JCM.03013-13. Epub 2013 Dec 26.
5
Analysis of human metapneumovirus and human bocavirus viral load.人偏肺病毒和人博卡病毒载量分析。
Pediatr Infect Dis J. 2013 Sep;32(9):1032-4. doi: 10.1097/INF.0b013e3182932f4f.
6
Acute human bocavirus 1 infection in child with life-threatening bilateral bronchiolitis and right-sided pneumonia: a case report.一名患有危及生命的双侧细支气管炎和右侧肺炎的儿童急性人博卡病毒1型感染：病例报告
J Med Case Rep. 2019 Sep 14;13(1):290. doi: 10.1186/s13256-019-2222-5.
7
Possible involvement of human bocavirus 1 in the death of a middle-aged immunosuppressed patient.可能与人博卡病毒 1 有关的中年免疫抑制患者死亡。
J Clin Microbiol. 2013 Oct;51(10):3461-3. doi: 10.1128/JCM.01157-13. Epub 2013 Jul 31.
8
Fatal human bocavirus infection in an 18-month-old child with chronic lung disease of prematurity.一名患有早产儿慢性肺病的18个月大儿童发生人博卡病毒致命感染。
Pediatr Infect Dis J. 2015 Jan;34(1):111-2. doi: 10.1097/INF.0000000000000509.
9
Severe Lower Respiratory Tract Infection Caused by Human Bocavirus 1 in an Infant.1型人博卡病毒引起的婴儿严重下呼吸道感染
Pediatr Infect Dis J. 2017 Nov;36(11):1107-1108. doi: 10.1097/INF.0000000000001681.
10
Detection of human bocavirus in the cerebrospinal fluid of children with encephalitis.检测脑炎患儿脑脊液中人博卡病毒。
Clin Infect Dis. 2012 Apr;54(7):964-7. doi: 10.1093/cid/cir957. Epub 2012 Jan 11.
引用本文的文献
1
Acute Human Bocavirus 1 Infection in Children Hospitalized for Acute Bronchiolitis: A 2-Year Prospective Study.因急性细支气管炎住院儿童的人博卡病毒1型急性感染：一项为期2年的前瞻性研究。
Pediatr Infect Dis J. 2025 Mar 1;44(3):195-199. doi: 10.1097/INF.0000000000004613. Epub 2024 Dec 4.
2
Life-Threatening Conditions in Children with Bocavirus Infection-Case Series and Mini Review of the Literature.儿童博卡病毒感染的危及生命情况——病例系列和文献复习。
Viruses. 2024 Aug 23;16(9):1347. doi: 10.3390/v16091347.
3
Breaking Bad: Inflammasome Activation by Respiratory Viruses.《绝命毒师》：呼吸道病毒引发的炎性小体激活
Biology (Basel). 2023 Jul 1;12(7):943. doi: 10.3390/biology12070943.
4
Human Bocavirus in Childhood: A True Respiratory Pathogen or a "Passenger" Virus? A Comprehensive Review.儿童人博卡病毒：真正的呼吸道病原体还是“过客”病毒？全面综述。
Microorganisms. 2023 May 9;11(5):1243. doi: 10.3390/microorganisms11051243.
5
Respiratory tract infection of fatal severe human bocavirus 1 in a 13-month-old child: A case report and literature review.一名13个月大儿童感染致命性严重人博卡病毒1型所致呼吸道感染：病例报告及文献综述
Front Pediatr. 2022 Dec 20;10:949817. doi: 10.3389/fped.2022.949817. eCollection 2022.
6
The small nonstructural protein NP1 of human bocavirus 1 directly interacts with Ku70 and RPA70 and facilitates viral DNA replication.人博卡病毒 1 的小非结构蛋白 NP1 与 Ku70 和 RPA70 直接相互作用，并促进病毒 DNA 复制。
PLoS Pathog. 2022 Jun 2;18(6):e1010578. doi: 10.1371/journal.ppat.1010578. eCollection 2022 Jun.
7
The Large Nonstructural Protein (NS1) of Human Bocavirus 1 Directly Interacts with Ku70, Which Plays an Important Role in Virus Replication in Human Airway Epithelia.人博卡病毒 1 的大非结构蛋白（NS1）与人呼吸道上皮细胞中的 Ku70 直接相互作用，Ku70 在病毒复制中发挥重要作用。
J Virol. 2022 Feb 23;96(4):e0184021. doi: 10.1128/JVI.01840-21. Epub 2021 Dec 8.
8
Prevalence and Genetic Characteristics of Human Bocaviruses Detected in Patients with Acute Respiratory Infections in Bulgaria.保加利亚急性呼吸道感染患者中检测到的人博卡病毒的流行情况及基因特征
Int J Microbiol. 2021 Nov 15;2021:7035081. doi: 10.1155/2021/7035081. eCollection 2021.
9
Hairpin Transfer-Independent Parvovirus DNA Replication Produces Infectious Virus.发夹转移非依赖细小病毒 DNA 复制产生感染性病毒。
J Virol. 2021 Sep 27;95(20):e0110821. doi: 10.1128/JVI.01108-21. Epub 2021 Aug 4.
10
A case report of pneumomediastinum in a COVID-19 patient treated with high-flow nasal cannula and review of the literature: Is this a "spontaneous" complication?一例接受高流量鼻导管治疗的COVID-19患者发生纵隔气肿的病例报告及文献综述：这是一种“自发性”并发症吗？
Clin Case Rep. 2021 Apr 9;9(5):e04007. doi: 10.1002/ccr3.4007. eCollection 2021 May.
本文引用的文献
1
Human bocavirus in children: mono-detection, high viral load and viraemia are associated with respiratory tract infection.儿童感染人博卡病毒：单重检测、高病毒载量和病毒血症与呼吸道感染有关。
J Clin Virol. 2010 Nov;49(3):158-62. doi: 10.1016/j.jcv.2010.07.016. Epub 2010 Sep 15.
2
Serologically verified human bocavirus pneumonia in children.血清学证实的儿童博卡病毒肺炎。
Pediatr Pulmonol. 2010 Feb;45(2):120-6. doi: 10.1002/ppul.21151.
3
The human bocaviruses: a review and discussion of their role in infection.人博卡病毒：对其在感染中作用的综述与讨论
Clin Lab Med. 2009 Dec;29(4):695-713. doi: 10.1016/j.cll.2009.07.010.
4
Human bocavirus DNA detected in a boy with plastic bronchitis.在一名患有塑料支气管炎的男孩体内检测到人类博卡病毒DNA。
Pediatr Infect Dis J. 2009 Nov;28(11):1035-6. doi: 10.1097/INF.0b013e3181ac4d0d.
5
Human Bocavirus quantitative DNA detection in French children hospitalized for acute bronchiolitis.对因急性细支气管炎住院的法国儿童进行人博卡病毒DNA定量检测。
J Clin Virol. 2008 Oct;43(2):142-7. doi: 10.1016/j.jcv.2008.05.010. Epub 2008 Jul 21.
6
Frequent detection of viral coinfection in children hospitalized with acute respiratory tract infection using a real-time polymerase chain reaction.采用实时聚合酶链反应对因急性呼吸道感染住院的儿童进行病毒合并感染的频繁检测。
Pediatr Infect Dis J. 2008 Jul;27(7):589-94. doi: 10.1097/INF.0b013e3181694fb9.
7
Respiratory viruses in HIV-infected patients with suspected respiratory opportunistic infection.疑似呼吸道机会性感染的HIV感染患者中的呼吸道病毒
AIDS. 2008 Mar 30;22(6):701-5. doi: 10.1097/QAD.0b013e3282f470ac.
8
Disseminated bocavirus infection after stem cell transplant.干细胞移植后播散性博卡病毒感染
Emerg Infect Dis. 2007 Sep;13(9):1425-7. doi: 10.3201/eid1309.070318.
9
Human bocavirus in children with acute lymphoblastic leukemia.急性淋巴细胞白血病患儿中的人博卡病毒
Eur J Pediatr. 2008 Sep;167(9):1011-5. doi: 10.1007/s00431-007-0631-8. Epub 2007 Nov 24.
10
Human bocavirus detection in an atopic child affected by pneumonia associated with wheezing.在一名患有与喘息相关肺炎的特应性儿童中检测到人博卡病毒。
J Clin Virol. 2007 Sep;40(1):43-5. doi: 10.1016/j.jcv.2007.06.011. Epub 2007 Aug 7.
Zotero 插件