Xu Chang-Lin, Shan Lu-Chen, Sun Ye-Wei, Wang Yu-Qiang
Institute of New Drug Research, Jinan University, Guangzhou 510632, China.
Zhong Yao Cai. 2010 Sep;33(9):1450-3.
To investigate the inhibitory effect of TBN on rabbit platelet aggregation in vitro and in vivo, and compare with tetramethylpyrazine (TMP).
To seek out the maximum of platelet aggregation (expressed in percentage) within 5 minutes which was induced by ADP, PAF and AA according to the Born turbidimetric method with a Platelet-Aggregometer.
TBN significantly inhibited platelet aggregation induced by ADP, PAF and AA both in vitro and in vivo. TBN was more active than TMP.
TBN has significant activity inhibiting platelet aggregation induced by ADP, PAF and AA in vitro and in vivo.
