Departamento de Química, Universidad Nacional de Colombia, AA 14490, Bogotá, Colombia.
J Agric Food Chem. 2011 Feb 9;59(3):975-83. doi: 10.1021/jf103151n. Epub 2011 Jan 18.
Ten flavonols and three anthocyanins were identified in the fruit peel of melón de olor (Sicana odorifera), and their structures were established by spectrometric and spectroscopic (ESI-MS and NMR) techniques. One of the identified flavonols, quercetin 3-O-(6''-O-malonyl)-β-D-glucopyranoside 4'-O-β-D-glucopyranoside, has not been reported before in the plant kingdom. Although quercetin-3-O-α-L-rhamnopyranosyl-(1→6)-β-d-glucopyranoside-4'-O-β-D-glucopyranoside had been reported before in literature and structure elucidation was done by comparison of NMR data with published data, to the best of our knowledge complete 1D and 2D NMR data have not been not delineated so far. Moreover, the antioxidant activity of pure compounds was measured by ABTS assay. It was established that quercetin 3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside, quercetin-3-O-(6''-malonyl)-glucopyranoside, quercetin-3-O-β-D-glucopyranoside, and quercetin-3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside-4'-O-β-D-glucopyranoside contribute significantly to the antioxidant activity exhibited by the fruit peel methanolic extract.
在香瓜（Sicana odorifera）的果皮中鉴定出 10 种类黄酮和 3 种花色苷，其结构通过光谱和光谱（ESI-MS 和 NMR）技术确定。鉴定出的一种类黄酮，槲皮素 3-O-（6''-O-丙二酰基）-β-D-吡喃葡萄糖苷 4'-O-β-D-吡喃葡萄糖苷，以前在植物界中尚未报道过。虽然槲皮素-3-O-α-L-鼠李吡喃糖苷基-（1→6）-β-D-吡喃葡萄糖苷-4'-O-β-D-吡喃葡萄糖苷以前在文献中有报道，并且通过与已发表数据的 NMR 数据比较进行了结构阐明，但据我们所知，迄今为止尚未完整描绘出 1D 和 2D NMR 数据。此外，通过 ABTS 测定法测量了纯化合物的抗氧化活性。结果表明，槲皮素 3-O-α-L-鼠李吡喃糖苷基-（1→6）-β-D-吡喃葡萄糖苷、槲皮素 3-O-（6''-丙二酰基）-吡喃葡萄糖苷、槲皮素 3-O-β-D-吡喃葡萄糖苷和槲皮素 3-O-α-L-鼠李吡喃糖苷基-（1→6）-β-D-吡喃葡萄糖苷-4'-O-β-D-吡喃葡萄糖苷对果皮甲醇提取物表现出的抗氧化活性有重要贡献。
