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重新审视院前气管插管的价值:提取 Utstein 气道核心变量的全时段系统文献回顾。

Revisiting the value of pre-hospital tracheal intubation: an all time systematic literature review extracting the Utstein airway core variables.

机构信息

Department of Research, The Norwegian Air Ambulance Foundation, Holterveien 24, PO Box 94, N-1441 Drøbak, Norway.

出版信息

Crit Care. 2011;15(1):R26. doi: 10.1186/cc9973. Epub 2011 Jan 18.

Abstract

INTRODUCTION

Although tracheal intubation (TI) in the pre-hospital setting is regularly carried out by emergency medical service (EMS) providers throughout the world, its value is widely debated. Heterogeneity in procedures, providers, patients, systems and stated outcomes, and inconsistency in data reporting make scientific reports difficult to interpret and compare, and the majority are of limited quality. To hunt down what is really known about the value of pre-hospital TI, we determined the rate of reported Utstein airway variables (28 core variables and 12 fixed-system variables) found in current scientific publications on pre-hospital TI.

METHODS

We performed an all time systematic search according to the PRISMA guidelines of Medline and EMBASE to identify original research pertaining to pre-hospital TI in adult patients.

RESULTS

From 1,076 identified records, 73 original papers were selected. Information was extracted according to an Utstein template for data reporting from in-the-field advanced airway management. Fifty-nine studies were from North American EMS systems. Of these, 46 (78%) described services in which non-physicians conducted TI. In 12 of the 13 non-North American EMS systems, physicians performed the pre-hospital TI. Overall, two were randomised controlled trials (RCTs), and 65 were observational studies. None of the studies presented the complete set of recommended Utstein airway variables. The median number of core variables reported was 10 (max 21, min 2, IQR 8-12), and the median number of fixed system variables was 5 (max 11, min 0, IQR 4-8). Among the most frequently reported variables were "patient category" and "service mission type", reported in 86% and 71% of the studies, respectively. Among the least-reported variables were "co-morbidity" and "type of available ventilator", both reported in 2% and 1% of the studies, respectively.

CONCLUSIONS

Core data required for proper interpretation of results were frequently not recorded and reported in studies investigating TI in adults. This makes it difficult to compare scientific reports, assess their validity, and extrapolate to other EMS systems. Pre-hospital TI is a complex intervention, and terminology and study design must be improved to substantiate future evidence based clinical practice.

摘要

简介

尽管气管插管(TI)在院前环境中由世界各地的紧急医疗服务(EMS)提供者定期进行,但它的价值存在广泛争议。程序、提供者、患者、系统和规定的结果存在异质性,数据报告不一致,使得科学报告难以解释和比较,而且大多数报告的质量有限。为了查明院前 TI 的真正价值,我们确定了当前关于院前 TI 的科学出版物中报告的 Utstein 气道变量(28 个核心变量和 12 个固定系统变量)的比率。

方法

我们根据 PRISMA 指南对 Medline 和 EMBASE 进行了全面的系统搜索,以确定与成人患者院前 TI 相关的原始研究。

结果

从 1076 条确定的记录中,选择了 73 篇原始论文。根据现场高级气道管理数据报告的 Utstein 模板提取信息。59 项研究来自北美 EMS 系统。其中,46 项(78%)描述的是由非医师进行 TI 的服务。在 13 个非北美 EMS 系统中,有 12 个由医师进行了院前 TI。总体而言,有 2 项为随机对照试验(RCT),65 项为观察性研究。没有一项研究报告了完整的推荐 Utstein 气道变量集。报告的核心变量中位数为 10 个(最大 21 个,最小 2 个,IQR 8-12),固定系统变量中位数为 5 个(最大 11 个,最小 0 个,IQR 4-8)。报告频率最高的变量是“患者类别”和“服务任务类型”,分别在 86%和 71%的研究中报告。报告频率最低的变量是“合并症”和“可用呼吸机类型”,分别在 2%和 1%的研究中报告。

结论

在调查成人 TI 的研究中,经常没有记录和报告正确解释结果所需的核心数据。这使得比较科学报告、评估其有效性和推断其他 EMS 系统变得困难。院前 TI 是一种复杂的干预措施,必须改进术语和研究设计,以支持未来基于证据的临床实践。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e3b2/3222062/df2a3cab1991/cc9973-1.jpg

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