Lucena R B, Rissi D R, Kommers G D, Pierezan F, Oliveira-Filho J C, Macêdo J T S A, Flores M M, Barros C S L
Department of Pathology, Laboratory of Veterinary Pathology, Universidade Federal de Santa Maria, Campus Camobi, 97105-900 Santa Maria, RS, Brazil.
J Comp Pathol. 2011 Jul;145(1):20-4. doi: 10.1016/j.jcpa.2010.11.002. Epub 2011 Jan 17.
Records from 6,706 necropsy examinations of cattle performed over a 45-year period were surveyed and 586 cases of neoplasia were identified. The organ system most frequently affected by neoplastic disease (n=139 cases) was the alimentary tract. This finding was attributed to a high incidence of squamous cell carcinoma of the upper alimentary tract associated with the chronic ingestion of bracken fern (Pteridium aquilinum). This carcinogenic plant was also associated with a relatively high incidence (n=35 cases) of urinary bladder tumours (enzootic haematuria). Tumours of the alimentary tract were followed, in decreasing order of frequency, by tumours of the skin and subcutis (n=129 cases), haemopoietic tissue (n=101 cases), the eye and periorbital tissues (n=88 cases), the urinary system (n=44 cases), the female reproductive system (n=21 cases), the endocrine system (n=16 cases), the liver and pancreas (n=12 cases), the nervous system (n=6 cases), the respiratory system (n=6 cases) and the mammary gland (n=1 case). The primary anatomical location of 16 tumours was undetermined.
对45年间进行的6706例牛尸检记录进行了调查，共识别出586例肿瘤病例。受肿瘤疾病影响最频繁的器官系统（n = 139例）是消化道。这一发现归因于上消化道鳞状细胞癌的高发病率，其与长期摄入蕨菜（蕨类植物）有关。这种致癌植物还与相对较高的膀胱肿瘤发病率（n = 35例）（地方性血尿）有关。消化道肿瘤之后，按频率递减顺序依次为皮肤和皮下组织肿瘤（n = 129例）、造血组织肿瘤（n = 101例）、眼及眶周组织肿瘤（n = 88例）、泌尿系统肿瘤（n = 44例）、女性生殖系统肿瘤（n = 21例）、内分泌系统肿瘤（n = 16例）、肝脏和胰腺肿瘤（n = 12例）、神经系统肿瘤（n = 6例）、呼吸系统肿瘤（n = 6例）和乳腺肿瘤（n = 1例）。16例肿瘤的原发解剖位置未确定。
