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颈动脉支架置入术同期冠状动脉旁路移植术

Same-Day Carotid Artery Stenting and Coronary Artery Bypass Surgery.

机构信息

Department of Cardiac Surgery, Dedinje Cardiovascular Institute, Belgrade, Serbia.

Cardiology Department, Mother and Child Health Institute of Serbia, Belgrade, Serbia.

出版信息

Tex Heart Inst J. 2023 Jan 1;50(1). doi: 10.14503/THIJ-21-7781.

Abstract

BACKGROUND

The optimal treatment strategy for patients with severe carotid artery disease undergoing coronary artery bypass grafting is still problematic. The important question is whether it is necessary to treat significant carotid disease in patients who have undergone coronary artery bypass grafting. This study analyzed short- and midterm results after same-day carotid artery stenting and coronary artery bypass grafting.

METHODS

From 2013 to 2020, a total of 69 patients were enrolled in the study. Same-day carotid artery stenting and coronary artery bypass grafting were performed in all patients. The study's primary end points were the evaluation rate of stroke, myocardial infarction, and death within short- and midterm periods after the procedures.

RESULTS

The 30-day mortality was 0%. The occurrences of perioperative adverse events, namely stroke, myocardial infarction, and transient ischemic attack, were 1 (1.4%), 1 (1.4%), and 4 (5.8%), respectively. Mean (IQR) follow-up time was 28 (IQR, 17-43) months. Six (8.8%) patients died during this period. Fatal stroke was registered in 2 cases, and 1 patient experienced a disabling stroke with a fatal outcome. The other 3 patients died because of chronic renal disease, a traffic accident, and for an unknown reason, respectively. Midterm survival in the group was 91.2%.

CONCLUSION

The study showed that same-day carotid artery stenting and coronary artery bypass grafting for concomitant carotid and coronary disease treatment could be a promising and feasible therapeutic strategy.

摘要

背景

行冠状动脉旁路移植术的重度颈动脉疾病患者的最佳治疗策略仍存在问题。重要的问题是,对于已经接受冠状动脉旁路移植术的患者,是否有必要治疗明显的颈动脉疾病。本研究分析了同期颈动脉支架置入术和冠状动脉旁路移植术的短期和中期结果。

方法

2013 年至 2020 年,共有 69 例患者入组本研究。所有患者均行同期颈动脉支架置入术和冠状动脉旁路移植术。本研究的主要终点是评估术后短期和中期内卒中、心肌梗死和死亡的发生率。

结果

30 天死亡率为 0%。围手术期不良事件(即卒中、心肌梗死和短暂性脑缺血发作)的发生率分别为 1(1.4%)、1(1.4%)和 4(5.8%)。平均(IQR)随访时间为 28(IQR,17-43)个月。在此期间,有 6 例(8.8%)患者死亡。2 例发生致命性卒中,1 例发生致残性卒中且结局致死。另外 3 例患者分别因慢性肾脏病、交通事故和未知原因死亡。该组患者的中期生存率为 91.2%。

结论

本研究表明,同期颈动脉支架置入术和冠状动脉旁路移植术治疗同时存在的颈动脉和冠状动脉疾病可能是一种有前途且可行的治疗策略。

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本文引用的文献

1
Midterm Results After Simultaneous Carotid Artery Stenting and Cardiac Surgery.同期颈动脉支架置入术和心脏手术的中期结果。
Ann Thorac Surg. 2020 Nov;110(5):1557-1563. doi: 10.1016/j.athoracsur.2020.02.051. Epub 2020 Apr 2.

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