National Center for Complementary and Alternative Medicine (NCCAM), National Institutes of Health, USA.
Curr Opin Psychiatry. 2011 Mar;24(2):149-55. doi: 10.1097/YCO.0b013e328343803b.
Considerable progress has been made in the neurobiological understanding of expectations in physiological and pathological processes. This article is aimed at presenting an overview of the role of expectations in producing health-related effects. We selected recent laboratory and clinical studies in the field of the placebo effect, with a particular focus on psychiatric disorders.
Recent scientific research indicates that expectations have the potential for relieving many symptoms. This research relies mostly on the study of placebo and nocebo phenomena which influence physiological and pathological functions. The findings from placebo and nocebo research have important implications for the design and interpretation of clinical trials and for clinical practice.
The studies of expectations in the field of psychiatry and in other fields of medicine suggest that placebo effects are likely to be an important aspect of any treatment. The application of research on health-related expectations has the potential for promoting wellness, improving health, and benefiting patient care.
目的综述:在生理和病理过程中对期望的神经生物学理解方面已经取得了相当大的进展。本文旨在概述期望在产生与健康相关的影响方面的作用。我们选择了安慰剂效应领域的最新实验室和临床研究,特别关注精神疾病。
发现:最近的科学研究表明,期望具有缓解许多症状的潜力。这项研究主要依赖于对安慰剂和反安慰剂现象的研究,这些现象影响着生理和病理功能。安慰剂和反安慰剂研究的结果对临床试验的设计和解释以及临床实践具有重要意义。
总结:精神病学领域和其他医学领域对期望的研究表明,安慰剂效应可能是任何治疗的一个重要方面。与健康相关的期望的研究应用有可能促进健康、改善健康并有益于患者护理。