Can Fam Physician. 1989 Oct;35:2061-5.
Chronic fatigue syndrome, previously known as chronic mononucleosis or post-infectious fatigue, is a poorly understood illness characterized by chronic debilitating fatigue, recurrent flu-like symptoms, and few clinical or laboratory abnormalities. Attention was briefly focused on the Epstein-Barr virus (EBV) as a causal agent, but that hypothesis is now in serious doubt. While a significant incidence of psychiatric illness has been demonstrated among patients with the chronic fatigue syndrome, there is also evidence of subtle immune system abnormalities, leading some researchers to postulate a multi-factorial psycho-immune cause.
慢性疲劳综合征,以前称为慢性单核细胞增多症或感染后疲劳,是一种病因不明的疾病,其特征为慢性虚弱性疲劳、反复发作的类似流感的症状和很少的临床或实验室异常。曾一度关注爱泼斯坦-巴尔病毒(EBV)作为致病因子,但该假说现在受到严重质疑。虽然在慢性疲劳综合征患者中已经证实存在相当高的精神疾病发病率,但也有证据表明存在微妙的免疫系统异常,这导致一些研究人员假设存在多因素的心理-免疫病因。