Radionecrosis of the larynx: case report and review of the literature.

Aim of the present report is to describe a case of radionecrosis related to radiotherapy of the larynx and to review the literature. A review was made of the hospital chart, surgery report, imaging studies and pathological findings of a 51-year-old male patient came to our attention. Results indicated that radionecrosis often requires total laryngectomy. It is very rare, but morbidity and mortality rates are high. The interval between conclusion of radiation therapy and development of radionecrosis ranges from 3 to 12 months. In this report, a case of radionecrosis is presented which has been managed using the organ sparing strategy. In conclusion, the larynx may be spared when radionecrosis occurs but more investigations are required in order to define the most appropriate treatment.