Universitat Rovira i Virgili, Research Centre for Behavioral Assessment (CRAMC), Department of Psychology, Ctra. Valls S/N, 43007 Tarragona, Spain.
Early Hum Dev. 2011 Mar;87(3):165-9. doi: 10.1016/j.earlhumdev.2010.12.006. Epub 2011 Jan 22.
Animal and human studies have shown that prenatal and postnatal iron deficiency is a risk factor for behavioral, emotional and cognitive development. The aim of this study was to determine the associations between iron status of pregnant women and the behavior of their newborn, taking into account the timing in which the deficit occurs. This study was conducted in Spain (developed country) where: the general population is well-nourished; during pregnancy routine obstetrical checks are carried out; and pregnant women are systematically iron supplemented. A total of 216 healthy and well-nourished pregnant women and their term, normal weight newborn participated in this study. The neonatal behavior was assessed by the Neonatal Behavior Assessment Scale (NBAS). The results showed that in the first and second trimesters of pregnancy, iron deficiency was a weak and significant predictor of the NBAS autonomous nervous system cluster score, and in the third trimester, this condition predicted the NBAS motor and state organization clusters score and the NBAS robustness and endurance supplementary item. In conclusion, iron deficiency during pregnancy is related to the neonate's general autonomous response, motor performance and self regulation capabilities.
动物和人体研究表明，产前和产后缺铁是行为、情绪和认知发育的一个风险因素。本研究旨在确定孕妇铁状况与新生儿行为之间的关系，同时考虑到缺铁发生的时间。本研究在西班牙进行（发达国家），那里：一般人群营养良好；怀孕期间进行常规产科检查；孕妇有系统的铁补充。共有 216 名健康和营养良好的孕妇及其足月、正常体重的新生儿参加了这项研究。新生儿行为通过新生儿行为评估量表（NBAS）进行评估。结果表明，在妊娠第一和第二阶段，缺铁是 NBAS 自主神经系统簇评分的一个微弱而显著的预测因素，而在妊娠第三阶段，这种情况预测了 NBAS 运动和状态组织簇评分以及 NBAS 稳健性和耐力补充项目。总之，怀孕期间缺铁与新生儿的一般自主反应、运动表现和自我调节能力有关。
