甲烷杆菌假肽聚糖与真细菌肽聚糖生物合成的比较。
Comparison of the biosynthesis of the methanobacterial pseudomurein and the eubacterial murein.
作者信息
Hartmann E, König H
机构信息
Abteilung für Angewandte Mikrobiologie und Mykologie der Universität, Ulm, Bundesrepublik Deutschland.
出版信息
Naturwissenschaften. 1990 Oct;77(10):472-5. doi: 10.1007/BF01135923.
PMID:2126345
Abstract
From cell extracts of the archaebacterium Methanobacterium thermoautotrophicum 11 putative precursors of the pseudomurein were isolated and characterized. On the basis of the isolated intermediates, a biosynthetic pathway of the pseudomurein is proposed. Compared to the eubacterial murein the biosynthetic stages follow different pathways as indicated by the occurrence of a nucleotide-activated disaccharide and nucleotide-activated peptides.
摘要
从嗜热自养甲烷杆菌的细胞提取物中分离并鉴定出11种假定的假肽聚糖前体。基于分离出的中间体，提出了假肽聚糖的生物合成途径。与真细菌的肽聚糖相比，生物合成阶段遵循不同的途径，这由核苷酸活化二糖和核苷酸活化肽的出现所表明。
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