Suppr超能文献

劳斯肉瘤病毒介导鸭细胞DNA序列向3T3细胞细胞核的转移。

Transfer of duck cell DNA sequences to the nucleus of 3T3 cells by Rous sarcoma virus.

作者信息

Baxt W G, Meinkoth J L

出版信息

Proc Natl Acad Sci U S A. 1978 Sep;75(9):4252-6. doi: 10.1073/pnas.75.9.4252.

Abstract

Peking duck cell nuclear DNA has no complementarity to RNA of Prague C Rous sarcoma virus (RSV). Upon infection of Peking duck cells by Prague C RSV, polynucleotide sequences complementary to Peking duck cell nuclear DNA can be detected in the high molecular weight RNA from progeny Peking duck cell passaged RSV (RSVPD) by RNA.DNA molecular hybridazation. When 3T3 cells are subsequently infected by RSVPD, polynucleotide sequences complementary to Peking duck cell nuclear DNA can be detected in the 3T3 cell nuclear DNA by RNA.DNA molecular hybridization. The potential consequences of the transfer of the Peking duck cell nuclear DNA from the avian to the murine cells are discussed.

摘要

北京鸭细胞核DNA与布拉格C型劳氏肉瘤病毒(RSV)的RNA没有互补性。在用布拉格C型RSV感染北京鸭细胞后,通过RNA-DNA分子杂交,可在子代北京鸭细胞传代RSV(RSVPD)的高分子量RNA中检测到与北京鸭细胞核DNA互补的多核苷酸序列。当3T3细胞随后被RSVPD感染时,通过RNA-DNA分子杂交,可在3T3细胞核DNA中检测到与北京鸭细胞核DNA互补的多核苷酸序列。本文讨论了北京鸭细胞核DNA从禽类细胞转移到鼠类细胞的潜在后果。

相似文献

5
Host induced alteration of avian sarcoma virus B-77 genome.宿主诱导的禽肉瘤病毒B-77基因组改变。
Proc Natl Acad Sci U S A. 1975 Mar;72(3):1031-5. doi: 10.1073/pnas.72.3.1031.

本文引用的文献

5
Analysis of repeating DNA sequences by reassociation.通过重缔合分析重复DNA序列。
Methods Enzymol. 1974;29:363-418. doi: 10.1016/0076-6879(74)29033-5.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验