基底细胞癌的非手术治疗选择。
Nonsurgical treatment options for Basal cell carcinoma.
作者信息
Lien Mary H, Sondak Vernon K
机构信息
Department of Dermatology and Cutaneous Surgery, University of South Florida College of Medicine, 12901 Bruce B. Downs Boulevard, Tampa, FL 33626, USA.
出版信息
J Skin Cancer. 2011;2011:571734. doi: 10.1155/2011/571734. Epub 2011 Jan 9.
Abstract
Basal cell carcinoma (BCC) remains the most common form of nonmelanoma skin cancer (NMSC) in Caucasians, with perhaps as many as 2 million new cases expected to occur in the United States in 2010. Many treatment options, including surgical interventions and nonsurgical alternatives, have been utilized to treat BCC. In this paper, two non-surgical options, imiquimod therapy and photodynamic therapy (PDT), will be discussed. Both modalities have demonstrated acceptable disease control rates, cosmetically superior outcomes, and short-term cost-effectiveness. Further studies evaluating long-term cure rates and long-term cost effectiveness of imiquimod therapy and PDT are needed.
摘要
基底细胞癌（BCC）仍是白种人中最常见的非黑色素瘤皮肤癌（NMSC）形式，预计2010年美国可能会出现多达200万例新病例。包括手术干预和非手术替代方案在内的许多治疗选择已被用于治疗基底细胞癌。在本文中，将讨论两种非手术选择，即咪喹莫特治疗和光动力疗法（PDT）。这两种方法均已证明具有可接受的疾病控制率、美容效果更佳以及短期成本效益。需要进一步研究评估咪喹莫特治疗和光动力疗法的长期治愈率和长期成本效益。
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