Department of Gynecology Oncology, Tehran University of Medical Sciences, Tehran, Iran.
J Gynecol Oncol. 2010 Dec 30;21(4):273-5. doi: 10.3802/jgo.2010.21.4.273. Epub 2010 Dec 31.
Sarcoma botryoides (embryonal rhabdomyosarcoma) rarely arises in the uterine cervix. We report a case of a 14-year-old female with sarcoma botryoides who presented with prolonged vaginal bleeding and cervical polyp. The biopsy specimen confirmed sarcoma botryoides. The patient underwent radical surgery of the tumor and hysterectomy without adjuvant chemotherapy. The sister of the patient had died previously due to the same diagnosis at the age of 17. We achieved a satisfactory outcome in short-term period with radical surgery and hysterectomy. Presence of sarcoma botryoides of the cervix in two sisters in the family highlights the possible role of genetic factors in the development of sarcoma botryoides.
葡萄状横纹肌肉瘤（胚胎性横纹肌肉瘤）很少发生于子宫颈。我们报告一例 14 岁女性患者，因葡萄状横纹肌肉瘤导致阴道出血时间延长和宫颈息肉。活检标本证实为葡萄状横纹肌肉瘤。患者接受了肿瘤根治性手术和子宫切除术，未行辅助化疗。患者的姐姐此前也因相同的诊断于 17 岁时死亡。我们通过根治性手术和子宫切除术获得了满意的短期疗效。两姐妹均患有宫颈葡萄状横纹肌肉瘤，提示遗传因素可能在葡萄状横纹肌肉瘤的发生中起作用。
