Department of Analytical and General Chemistry, Faculty of Pharmacy, Istanbul University, Istanbul, Turkey.
Pharm Biol. 2011 Mar;49(3):290-5. doi: 10.3109/13880209.2010.517539. Epub 2011 Feb 2.
Consumers have become more interested in beneficial effects of vegetables, fruits, and tea to protect their health.
The antioxidant potential and anticholinesterase activity of eleven edible plants were investigated.
The dichloromethane, ethanol and water extracts prepared from celery [Apium graveolens L. (Umbelliferae)], Jerusalem artichoke [Helianthus tuberosus L. (Compositae)], spinach [Spinacia oleracea L. (Chenopodiaceae)], chard [Beta vulgaris L. var. cicla (Chenopodiaceae)], purslane [Portulaca oleracea L. (Portulacaceae)], ispit, or borage [Trachystemon orientale (L.) G. Don (Boraginaceae)], garden rocket [Eruca sativa Mill. (Brassicaceae)], red cabbage [Brassica oleracea L. var. capitata f. rubra DC. (Cruciferae)], lime flower [Tilia tomentosa Moench (Tiliaceae)], cinnamon [Cinnamomum cassia Presl. (Lauraceae)], and rosehip [Rosa canina L. (Rosaceae)], were tested to determine their antioxidant and anticholinesterase activities by using CUPRAC (cupric reducing antioxidant capacity) and Ellman methods, respectively, for the first time.
As a result, the dichloromethane, ethanol and water extracts of cinnamon showed the best antioxidant effect among the extracts of the tested plants. The ethanol extract of cinnamon exhibited 63.02% inhibition against acetylcholinesterase and 85.11% inhibition against butyrylcholinesterase (BChE) at 200 µg/mL concentration while the dichloromethane extract of garden rocket possessed the highest inhibition (91.27%) against BChE among all the tested extracts.
This study indicated that the ethanol extract of cinnamon may be a new potential resource of natural antioxidant and anticholinesterase compounds.
消费者对蔬菜、水果和茶的有益健康的功效越来越感兴趣。
研究了 11 种食用植物的抗氧化潜力和乙酰胆碱酯酶抑制活性。
首次从芹菜（伞形科）、菊芋（菊科）、菠菜（藜科）、菠菜（藜科）、马齿苋（马齿苋科）、豆瓣菜（十字花科）、西洋菜（车前草科）、花园火箭（十字花科）、红甘蓝（芸苔科）、酸橙花（椴树科）、肉桂（樟科）和玫瑰果（蔷薇科）中制备了二氯甲烷、乙醇和水提取物，以测定其抗氧化和乙酰胆碱酯酶活性，分别采用 CUPRAC（铜还原抗氧化能力）和 Ellman 方法。
结果表明，肉桂的二氯甲烷、乙醇和水提取物在测试植物的提取物中表现出最好的抗氧化效果。肉桂的乙醇提取物在 200μg/ml 浓度下对乙酰胆碱酯酶的抑制率为 63.02%，对丁酰胆碱酯酶（BChE）的抑制率为 85.11%，而花园火箭的二氯甲烷提取物在所有测试提取物中对 BChE 的抑制率最高（91.27%）。
本研究表明，肉桂的乙醇提取物可能是天然抗氧化剂和乙酰胆碱酯酶抑制剂的新潜在资源。
