Tanner K E
School of Engineering, James Watt South Building, University of Glasgow, Glasgow G12 8QQ, UK.
Proc Inst Mech Eng H. 2010 Dec;224(12):1359-72. doi: 10.1243/09544119JEIM823.
One of the major challenges for bone tissue engineering is the production of a suitable scaffold material. In this review the currently available composite material options are considered and the methods of production and assessing the scaffolds are also discussed. The production routes range from the use of porogens to produce the porosity through to controlled deposition methods. The testing regimes include mechanical testing of the produced materials through to in vivo testing of the scaffolds. While the ideal scaffold material has not yet been produced, progress is being made.
骨组织工程面临的主要挑战之一是生产合适的支架材料。在这篇综述中，我们考虑了目前可用的复合材料选项，并讨论了支架的生产方法和评估方法。生产途径从使用致孔剂产生孔隙到控制沉积方法。测试方案包括对所生产材料的力学测试以及对支架的体内测试。虽然尚未生产出理想的支架材料，但正在取得进展。
