Whittle D O, Ewing R, Lee M G
Department of Medicine, The University of the West Indies, Kingston 7, Jamaica, West Indies.
West Indian Med J. 2010 Jun;59(3):309-11.
Helicobacter pylori infection remains a common problem and previous studies in the Caribbean revealed infection in over 50% of patients undergoing upper endoscopy.
The present study determined the prevalence of H pylori infection in patients undergoing upper gastrointestinal endoscopy in the Turks and Caicos Islands over a two- year interval.
All patients with upper gastrointestinal symptoms requiring endoscopy were evaluated clinically and H pylori testing performed histologically.
There were 57 patients (21 males, 36 females) with a mean age of 43 years. Twenty-six patients presented with gastroesophageal reflux, 17 with upper abdominal pain, 10 with dyspepsia and 4 with upper gastrointestinal bleeding. H pylori infection was present in 24 patients (42%) and negative in 33 (58%). Upper gastrointestinal endoscopy was normal in 27 patients, 13 (54%) were H pylori positive and 14 (43%) negative. Antral gastritis was present in 13 patients, 7 (54%) were H pylori positive and 6 (46%) negative. Duodenal ulcer was present in 6 (33% H pylori positive) and gastric ulcer in 5 patients (40% H pylori positive). Distal oesophagitis was present in 5 patients (all negative for H pylori) and gastric carcinoma in 1 (H pylori positive).
In patients with dyspepsia, 60% were positive for H pylori. H pylori infection was common in the patients in this study with gastrointestinal symptoms. However, the prevalence in endoscopic patients and peptic ulcer disease is lower than in other reports from the Caribbean.
幽门螺杆菌感染仍然是一个常见问题，先前在加勒比地区的研究显示，接受上消化道内镜检查的患者中超过50%存在感染。
本研究确定了特克斯和凯科斯群岛在两年时间间隔内接受上消化道内镜检查的患者中幽门螺杆菌感染的患病率。
对所有有上消化道症状需要内镜检查的患者进行临床评估，并通过组织学方法进行幽门螺杆菌检测。
共有57例患者（21例男性，36例女性），平均年龄43岁。26例患者表现为胃食管反流，17例表现为上腹部疼痛，10例表现为消化不良，4例表现为上消化道出血。24例患者（42%）存在幽门螺杆菌感染，33例（58%）为阴性。27例患者上消化道内镜检查正常，其中13例（54%）幽门螺杆菌阳性，14例（43%）阴性。13例患者存在胃窦炎，7例（54%）幽门螺杆菌阳性，6例（46%）阴性。6例患者患有十二指肠溃疡（33%幽门螺杆菌阳性），5例患者患有胃溃疡（40%幽门螺杆菌阳性）。5例患者存在远端食管炎（均为幽门螺杆菌阴性），1例患者患有胃癌（幽门螺杆菌阳性）。
在消化不良患者中，60%幽门螺杆菌呈阳性。本研究中有胃肠道症状的患者中幽门螺杆菌感染很常见。然而，内镜检查患者和消化性溃疡疾病中的患病率低于加勒比地区的其他报告。
