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[卡他布兰汉菌呼吸道感染]

[Branhamella catarrhalis respiratory tract infections].

作者信息

Letonja S, Music E, Kumelj M

机构信息

Splosna bolnisnica, Pljucni oddelek, Maribor.

出版信息

Plucne Bolesti. 1990 Jul-Dec;42(3-4):144-7.

PMID:2129309
Abstract

Forty-six hospitalised patients with respiratory tract infections (RTI) in whom Branhamella catarrhalis had been isolated were evaluated. On average they were 70 years old, there were 39 males and 7 females, 89% of them were smokers. In 85% Branhamella catarrhalis caused exacerbation of chronic bronchitis and in 15% the pneumonia. Most cases of this infection were detected in December and January. In vitro 78% of strains formed beta lactamasis. All 46 isolations were sensitive to cyprofloxacin, 43 (93%) to the combination of amoxicillin with clavulanic acid, 41% (89.1%) to erithromycin, 44 (95.6%) to gentamycin and only 26 (56.5%) to trimetoprim-sulphametoxasol. In the therapy amoxicillin with clavulanic acid, macrolids and kinolons were successful while trimetroprim-sulphametoxasol was less effective.

摘要

对46例分离出卡他布兰汉菌的呼吸道感染住院患者进行了评估。他们的平均年龄为70岁,其中男性39例,女性7例,89%为吸烟者。85%的病例中卡他布兰汉菌导致慢性支气管炎加重,15%导致肺炎。这种感染的大多数病例在12月和1月被检测到。体外试验中,78%的菌株产生β-内酰胺酶。所有46株分离菌对环丙沙星敏感,43株(93%)对阿莫西林与克拉维酸的联合制剂敏感,41%(89.1%)对红霉素敏感,44株(95.6%)对庆大霉素敏感,而对甲氧苄啶-磺胺甲恶唑敏感的仅有26株(56.5%)。在治疗中,阿莫西林与克拉维酸、大环内酯类和喹诺酮类药物治疗成功,而甲氧苄啶-磺胺甲恶唑效果较差。

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