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古巴住院儿童贾第虫感染的危险因素。

Risk factors for Giardia infection among hospitalized children in Cuba.

作者信息

Bello J, Núñez F A, González O M, Fernández R, Almirall P, Escobedo A A

机构信息

Academic Paediatric Hospital of Cerro, Calzada del Cerro No. 2002, Cerro, Ciudad de La Habana, Cuba.

出版信息

Ann Trop Med Parasitol. 2011 Jan;105(1):57-64. doi: 10.1179/136485911X12899838413385.

Abstract

The risk factors associated with Giardia infection, in children hospitalized in Havana, Cuba, were recently explored. Children aged ≥5 years were more likely to be positive for Giardia infection than the younger children, with an odds ratio (OR) of 3·41 [95% confidence interval (CI) = 1·36-9·69]. The risk factors found to be associated with Giardia infection in univariate analyses were rural residence (OR = 3·01; CI = 1·23-7·35), belonging to a household that did not receive water from an aqueduct (OR = 3·27; CI = 1·21-8·91), drinking unboiled water (OR = 3·64; CI = 2·14-6·26), nail biting (OR = 3·47; CI = 1·97-6·08), eating unwashed vegetables raw (OR = 4·84; CI = 2·33-10·14), and a personal (OR = 3·23; CI = 1·58-6·59) or family history (OR = 3·96; CI = 1·53-10·47) of previous parasitic infection. In multivariate analyses, however, only two (modifiable) risk factors were found to be independently and significantly associated with Giardia infection: nail biting and eating unwashed vegetables raw. It therefore seems that, at least at the individual level, giardiasis-prevention activities in Havana should be focussed on health education to improve personal hygiene and food-related practices. If appropriately managed, the surveillance of drinking water and foodstuffs, for Giardia and other parasites, might also help to reduce the hospitalization of Cuban children.

摘要

近期对古巴哈瓦那住院儿童中与贾第虫感染相关的危险因素进行了探究。5岁及以上儿童贾第虫感染呈阳性的可能性高于年幼儿童,优势比(OR)为3.41[95%置信区间(CI)=1.36 - 9.69]。单因素分析中发现与贾第虫感染相关的危险因素有:农村居住(OR = 3.01;CI = 1.23 - 7.35)、家庭未接入自来水(OR = 3.27;CI = 1.21 - 8.91)、饮用生水(OR = 3.64;CI = 2.14 - 6.26)、咬指甲(OR = 3.47;CI = 1.97 - 6.08)、生食未清洗蔬菜(OR = 4.84;CI = 2.33 - 10.14)以及个人(OR = 3.23;CI = 1.58 - 6.59)或家族有既往寄生虫感染史(OR = 3.96;CI = 1.53 - 10.47)。然而,多因素分析中仅发现两个(可改变的)危险因素与贾第虫感染独立且显著相关:咬指甲和生食未清洗蔬菜。因此,至少在个体层面,哈瓦那的贾第虫病预防活动应侧重于健康教育以改善个人卫生和与食物相关的行为习惯。如果管理得当,对饮用水和食品进行贾第虫及其他寄生虫监测也可能有助于减少古巴儿童的住院率。

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