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[利用胆囊行胆胰分流术治疗慢性胰腺炎。85例胆囊成形术]

[Bilio-digestive bypass using gallbladder in chronic pancreatitis. 85 cases of cholecystoplasty ].

作者信息

Vankemmel M, Martin F, Baspeyre H, Dupuys F

机构信息

Service de Chirurgie digestive, hôpital Huriez, CHU, Lille.

出版信息

Chirurgie. 1990;116(8-9):742-51.

PMID:2129991
Abstract

For a group of 368 cases of chronic pancreatitis (CP) operated on since 1975, the authors have performed 85 biliary intestinal anastomoses using the gallbladder, for treatment of biliary obstruction. (These were cases not needing resection of the head of the pancreas). This original biliary-intestinal by-pass comprises resection of the cystic duct then bridging the gallbladder between the common bile duct and the duodenum (in 2 cases the jejunum). This anastomosis of common bile duct to infundibulum was termino-terminal except in 15 where portal vein dilatation necessitated a latero-terminal anastomosis. The gallbladder-intestinal anastomoses were termino-lateral. One patient with multi-system disease died on the 20th post-op day from cardio-respiratory problems not directly related to the procedure. No fistulae, biliary or intestinal occurred. The average hospitalization was 13.6 days. The average follow-up period is now 46 months (2 patients only have been lost to follow-up). One patient (not abstaining from alcohol) has presented with recurrent febrile episodes and transient alkaline phosphatase elevations. Two patients only have been re-operated (9th and 72nd months) for cholangiocholitis necessitating a re-do of the anastomosis infundibulum to bile duct. These 2 patients are well at 20 and 45 months respectively. No biliary calculi have been observed, with 22% of patients now being more than 5 years post-op. The authors have progressively left aside the anastomosis to a jejunal loop in favour of the gallbladder interposition described. This appears a better procedure for treating biliary obstruction in chronic pancreatitis even when complicated by portal vein dilatation. This procedure enables drainage of bile into its natural site at the 2nd part of the duodenum, so reducing the risk of ulceration. It also saves extending the operating field below the mesocolon and importantly in the already poorly nourished patient, it does not remove from function a segment of jejunum.

摘要

自1975年以来,作者对368例慢性胰腺炎(CP)患者进行了手术治疗,其中85例采用胆囊进行胆肠吻合术,以治疗胆道梗阻。(这些病例不需要切除胰头)。这种原始的胆肠旁路手术包括切除胆囊管,然后将胆囊连接在胆总管和十二指肠之间(2例连接至空肠)。胆总管与胆囊漏斗部的吻合除15例因门静脉扩张需行侧端吻合外,其余均为端端吻合。胆囊与肠道的吻合为端侧吻合。1例多系统疾病患者术后第20天因与手术无直接关系的心肺问题死亡。未发生胆瘘或肠瘘。平均住院时间为13.6天。目前平均随访期为46个月(仅2例失访)。1例(未戒酒)出现反复发热和短暂碱性磷酸酶升高。仅2例患者因胆管炎在术后第9个月和第72个月再次手术,需要重新进行胆囊漏斗部与胆管的吻合。这2例患者分别在术后20个月和45个月情况良好。未观察到胆石形成,22%的患者术后已超过5年。作者逐渐放弃了与空肠袢吻合,而倾向于采用所述的胆囊置入术。对于治疗慢性胰腺炎合并胆道梗阻,即使伴有门静脉扩张,该手术似乎也是一种更好的方法。该手术可使胆汁引流至十二指肠第二部的自然部位,从而降低溃疡风险。它还避免了将手术视野扩展至结肠系膜下方,重要的是,对于营养状况本就不佳的患者,它不会使一段空肠失去功能。

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