Centre for Public Health, Liverpool John Moores University, Henry Cotton Campus (third floor), 15-21 Webster Street, Liverpool L3 2ET, UK.
BMC Pediatr. 2011 Feb 8;11:14. doi: 10.1186/1471-2431-11-14.
Internationally, 0.97 per 1,000 live births are affected by foetal alcohol syndrome (FAS). However, prevalence intelligence has been limited in the UK, hindering the development of appropriate services. This analysis compares hospital admissions over time, between regions and with alcohol-related admissions for adult females to assess whether established patterns (such as the North experiencing elevated harms) can be identified.
A retrospective analysis of hospital admissions data (April 2002 to March 2008) for foetal alcohol spectrum disorder (FASD)-related conditions: foetal alcohol syndrome (dysmorphic) (n = 457); foetus and newborn affected by maternal use of alcohol (n = 157); maternal care for (suspected) damage to foetus from alcohol (n = 285); and 322,161 women admitted due to alcohol-related conditions.
Whilst the rate of admission for alcohol-related conditions in women aged 15-44 years increased significantly by 41% between 2002/03 and 2007/08 (p < 0.0001), no such increases were seen in the numbers of FASD-related conditions (all p < 0.05). Established regional rates of admission for alcohol-related conditions in women aged 15-44 years old were not associated with admission for FASD-related conditions.
It would be expected that the North West and North East regions, known to have higher levels of alcohol harm would have higher levels of FASD-related conditions. However, this was not reflected in the incidence of such conditions, suggesting under-reporting. With incomplete datasets, intelligence systems are severely limited, hampering efforts to develop targeted interventions. Improvements to intelligence systems, practitioner awareness and screening are essential in tackling this.
在国际上,每千例活产中就有 0.97 例受到胎儿酒精综合征(FAS)的影响。然而,英国的流行率数据有限,这阻碍了相关服务的发展。本分析比较了一段时间内、不同地区以及与酒精相关的成年女性住院情况,以评估是否可以确定已建立的模式(例如,北方地区的危害程度较高)。
对与胎儿酒精谱系障碍(FASD)相关的住院数据(2002 年 4 月至 2008 年 3 月)进行回顾性分析:胎儿酒精综合征(畸形)(n = 457);受母亲酒精使用影响的胎儿和新生儿(n = 157);因母亲怀疑胎儿受到酒精损害而接受的护理(n = 285);以及因酒精相关疾病而住院的 322,161 名女性。
尽管 15-44 岁女性因酒精相关疾病的住院率在 2002/03 年至 2007/08 年间显著增加了 41%(p < 0.0001),但 FASD 相关疾病的数量并未增加(均 p < 0.05)。15-44 岁女性的酒精相关疾病的既定地区入院率与 FASD 相关疾病的入院率无关。
预计已知酒精危害水平较高的西北地区和东北地区会有更高水平的 FASD 相关疾病。然而,这种情况并未反映在这些疾病的发病率上,这表明报告不足。由于数据不完整,情报系统受到严重限制,阻碍了制定有针对性干预措施的努力。改善情报系统、提高从业人员意识和筛查是解决这一问题的关键。