Praticò A D, Saporito M, Iacono O, Castellano-Chiodo D, Pavone P
Department of Pediatrics, University of Catania, Catania.
Minerva Pediatr. 2011 Feb;63(1):73-78.
Subacute sclerosing panencephalitis (SSPE) is a progressive neurological disorder of childhood and early adolescence caused by persistent defective measles virus. Clinical manifestations appear many years after the acute measles infection. The incidence of SSPE has substantially declined after the introduction of an effective vaccine. We report a case of a child with SSPE that began with atonia, dysarthria, and intellectual deterioration without the presence of any particular EEG anomalies. We have reported this girl who was affected by this severe affliction in the hope that, because of the rarity of SSPE, it would not go undiagnosed.
亚急性硬化性全脑炎（SSPE）是一种由持续性缺陷麻疹病毒引起的儿童和青少年早期的进行性神经疾病。临床表现出现在急性麻疹感染多年之后。有效疫苗问世后，SSPE的发病率大幅下降。我们报告一例亚急性硬化性全脑炎患儿，起病表现为肌张力缺失、构音障碍和智力衰退，且无任何特定的脑电图异常。我们报告了这名受此严重疾病影响的女孩，希望鉴于SSPE的罕见性，它不会被漏诊。
