Sundar S, Wagle N, Varudkar B L, Vaidya A, Merchant S M
Microbiology Section, Bai Jerbai Wadia Hospital for Children, Parel, Bombay.
Indian J Pediatr. 1990 Nov-Dec;57(6):763-70. doi: 10.1007/BF02722271.
The study was done to determine IgG and IgM antitetanus antibodies in mothers after antenatal immunization, and extent of transfer to the baby as measured by cord levels of tetanus specific IgG and IgM by ELISA using enzyme penicillinase and to study the effect of nutritional status of mothers on antibody response to tetanus toxoid and corresponding cord levels also to determine the number of doses required for protective antibody levels in cord blood. The results obtained in sera of 100 mothers at the time of delivery and their respective cord sera and results of 43 different control sera are discussed using ELISA technique.
本研究旨在测定产前免疫后母亲体内的IgG和IgM抗破伤风抗体，以及通过酶联免疫吸附测定法（ELISA）使用酶青霉素酶检测脐带血中破伤风特异性IgG和IgM水平来衡量抗体向婴儿的转移程度，并研究母亲营养状况对破伤风类毒素抗体反应及相应脐带血水平的影响，同时确定脐带血中产生保护性抗体水平所需的剂量。使用ELISA技术讨论了100名母亲分娩时血清及其各自脐带血清的检测结果以及43份不同对照血清的结果。
