Queen's University Belfast, David Keir Building, Stranmillis Road, Belfast BT9 5AG, UK.
Trends Biotechnol. 2011 May;29(5):199-204. doi: 10.1016/j.tibtech.2011.01.005. Epub 2011 Feb 15.
In the future, biomass will continue to emerge as a viable source of chemicals. The development of new industries that utilize bio-renewables provides opportunities for innovation. For example, bio- and chemo-catalysts can be combined in 'one pot' to prepare chemicals of commercial value. This has been demonstrated using isolated enzymes and whole cells for a variety of chemical transformations. The one-pot approach has been successfully adopted to convert chemicals derived from biomass, and, in our opinion, it has an important role to play in the design of a more sustainable chemical industry. To implement new one-pot bio- and chemo-catalytic processes, issues of incompatibility must be overcome; the strategies for which are discussed in this opinion article.
在未来，生物质将继续成为一种可行的化学品来源。开发利用生物可再生资源的新产业为创新提供了机会。例如，可以将生物和化学催化剂“一锅法”组合起来制备具有商业价值的化学品。这已经通过使用各种化学转化的分离酶和完整细胞得到了证明。这种“一锅法”已成功应用于转化源自生物质的化学品，并且，我们认为，它在设计更可持续的化学工业方面具有重要作用。为了实施新的“一锅法”生物和化学催化工艺，必须克服不兼容性问题；本文讨论了应对这些问题的策略。
