Regional Medical Physics Department, Freeman Hospital, Newcastle upon Tyne NE77DN, UK.
Physiol Meas. 2011 Mar;32(3):359-67. doi: 10.1088/0967-3334/32/3/007. Epub 2011 Feb 18.
This study investigated the interaction between heart rate (HR) and blood pressure (BP) during conscious control under visual biofeedback and background noise conditions. Normotensive volunteers were instructed to (i) decrease and (ii) increase HR (group A, n = 16) or BP (group B, n = 16). After instructions to lower HR or BP there was no significant change in HR or BP for either group. After instructions to raise HR, HR increased significantly (13.8 ± 1.3 beats min⁻¹, P < 0.0001) and BP did not change. However, following instructions to raise BP, both HR and BP increased significantly: systolic BP (5.2 ± 1.5 mmHg, P < 0.001), diastolic BP (3.5 ± 0.9 mmHg, P < 0.001) and HR (8.6 ± 1.3 beats min⁻¹, P < 0.0001). Biofeedback and background noise did not alter the relative change in HR or BP. In conclusion, normotensive subjects were unable to reduce BP or HR under conscious control. Subjects were able to increase both HR and BP, and voluntary increases in HR did not alter BP, while voluntary increases in BP also increased HR indicating distinct HR/BP interactions during conscious control.
本研究探讨了在视觉生物反馈和背景噪声条件下有意识控制下心率 (HR) 和血压 (BP) 之间的相互作用。 正常血压志愿者被指示（i）降低和（ii）增加 HR（A 组，n = 16）或 BP（B 组，n = 16）。 在降低 HR 或 BP 的指示后，两组的 HR 或 BP 均无明显变化。 在指示升高 HR 后，HR 显著升高（13.8 ± 1.3 次/分钟，P < 0.0001），BP 没有变化。 然而，在指示升高 BP 后，HR 和 BP 均显著升高：收缩压（5.2 ± 1.5 mmHg，P < 0.001），舒张压（3.5 ± 0.9 mmHg，P < 0.001）和 HR（8.6 ± 1.3 次/分钟，P < 0.0001）。 生物反馈和背景噪声并没有改变 HR 或 BP 的相对变化。 总之，正常血压的受试者在有意识的控制下无法降低血压或心率。 受试者能够升高 HR 和 BP，并且 HR 的自愿升高不会改变 BP，而 BP 的自愿升高也会升高 HR，这表明在有意识的控制期间存在明显的 HR/BP 相互作用。
