Yoshida Eye Hospital, Hakodate, Japan.
Jpn J Ophthalmol. 2011 Jan;55(1):62-6. doi: 10.1007/s10384-010-0901-2. Epub 2011 Feb 18.
To investigate the effects of light scattering from the surface of hydrophobic acrylic intraocular lenses (IOLs) on visual function.
A 67-year-old man was implanted with an IOL (MA60BM) in January 1998, but became aware of decreased visual function in May 2008. Observation with a slit lamp revealed light scattering throughout the entire optic of the IOL, which was extracted and replaced. Postoperative visual function improved at 1 month. The cause of light scattering was investigated with a focus on water permeating the IOL material. To confirm the effect of light scattering on visual function, light transmission of the extracted IOL was measured in physiological saline at 33 °C, and the simulated retinal image was evaluated in a model eye.
Observation of the extracted IOL showed light scattering from the optic surface layer, the main cause of which was phase-separated water within the IOL material. Light transmission in the extracted IOL was 16.3% lower than that in an unused IOL in the visible range. Moreover, the simulated retinal image was hazy compared to that of the unused IOL.
Severe surface light scattering from an IOL optic may decrease visual function.
研究疏水丙烯酸人工晶状体（IOL）表面光散射对视觉功能的影响。
一位 67 岁男性于 1998 年 1 月植入 IOL（MA60BM），但在 2008 年 5 月发现视力下降。裂隙灯观察发现整个 IOL 光学区有光散射，于是将其取出并更换。术后 1 个月视力改善。重点研究了水渗透 IOL 材料的原因，对光散射的原因进行了调查。为了确认光散射对视觉功能的影响，在 33°C 的生理盐水中测量了提取的 IOL 的光透过率，并在模型眼中评估了模拟视网膜图像。
对提取的 IOL 进行观察，发现从光学表面层散射出光线，其主要原因是 IOL 材料内的相分离水。提取的 IOL 在可见光范围内的光透过率比未使用的 IOL 低 16.3%。此外，与未使用的 IOL 相比，模拟视网膜图像较为模糊。
IOL 光学面严重的表面光散射可能会降低视觉功能。
