Rehman Jamil, Sangalli Mattia N, Guru Khurshid, de Naeyer Geert, Schatteman Peter, Carpentier Paul, Mottrie Alexander
Department of Urology, SUNY-Stony Brook University Health Sciences Center, School of Medicine, New York, USA.
Can J Urol. 2011 Feb;18(1):5548-56.
Several recent preliminary reports have demonstrated that Robot-Assisted Cystectomy with total intracorporeal Ileal Conduit (RACIC) is a feasible option over the open technique. We report our stepwise surgical procedure of robotic total intracorporeal ileal conduit urinary diversion, technical consideration, development, refinements and initial experience. Only the ileal conduit urinary diversion is described with no emphasis on the cystectomy's steps.
Between February 2008 and September 2009, nine patients underwent RACIC for muscle invasive transitional cell carcinoma (TCC). The entire procedure, including radical cystoprostatectomy, extended pelvic node dissection (ePLND), ileal conduit urinary diversion (Bricker) including isolation of the ileal loop (20 cm ileal segment) 15 cm away from the ileocecal junction, restoration of bowel continuity with stapled side-to-side ileo-ileal anastomosis, retroperitoneal transfer of the left ureter to the right side, and bilateral stented (8 F feeding tube) ileo-ureteral anastomoses in a Wallace faction were all performed exclusively intracorporeally using the da Vinci Si surgical robot and finally the conduit stoma was fashioned.
The RACIC was technically successful in all nine patients (three females and six males. Mean age 74.1; 57 to 87) without open conversion. The mean operative time including extended pelvic lymphadenectomy and urinary diversion was 346.2 minutes (210 to 480). Mean operative time of diversion is 72 minutes (52-113) mean estimated blood loss 258 mL (200 to 500) and the median hospital stay were 14 days (10 to 27). In all three female patients, the specimen was extracted through the vagina. There were no intraoperative complications and only one major postoperative complication: one postoperative iatrogenous necrosis of the ileal conduit caused by uncareful retraction of the organ bag and thereby probably injuring the conduit pedicle, as the ileal conduit was well vascularised at the end of the operation, requiring an open revision (in male patient extracted through the suprapubic incision). A clear liquid diet was started on the third postoperative day. All patients returned to normal activity within 2 weeks (from date of surgery). Postoperative renal function was normal with mean postoperative creatine 0.99 mg/dL) and excretory urography revealed unobstructed upper tracts in all cases.
Robot-assisted radical cystoprostatectomy with intracorporeal ileal conduit urinary diversion for the treatment of high risk or invasive bladder cancer with urinary diversion is technically feasible. The robotic system aids in performing a meticulous dissection and all operative steps of the open procedure are replicated precisely while adhering to the sound oncologic principles of traditional radical cystectomy. Robotics brings an unprecedented control of surgical instruments, shorten the learning curve, and allow open surgeons to apply more easily their technical skill in a minimal invasive fashion. Robotic cystectomy with total intracorporeal ileal conduit urinary diversion offers operative and perioperative benefits and functional outcome. In our hands results comparable to open experience with further reduced perioperative morbidity, early recovery, resumption of normal activities, excellent cosmesis and increased quality of life (QOL). In addition, minimal blood loss, fluid shifts, and electrolyte loss considerably reduce systemic and cardiovascular stress in these older groups of patients.
近期的几份初步报告表明,机器人辅助全体内置回肠膀胱术(RACIC)是一种优于开放手术的可行选择。我们报告了机器人全体内置回肠膀胱尿流改道术的分步手术过程、技术考量、发展、改进及初步经验。本文仅描述回肠膀胱尿流改道术,未着重介绍膀胱切除术步骤。
2008年2月至2009年9月期间,9例肌肉浸润性移行细胞癌(TCC)患者接受了RACIC手术。整个手术过程,包括根治性膀胱前列腺切除术、扩大盆腔淋巴结清扫术(ePLND)、回肠膀胱尿流改道术(Bricker术),即离回盲部15厘米处游离回肠袢(20厘米回肠段)、用吻合器行端端回肠吻合恢复肠道连续性、将左输尿管腹膜后转移至右侧、在Wallace术式中双侧置入支架(8F喂养管)行回肠输尿管吻合,均仅通过达芬奇Si手术机器人在体内完成,最后形成膀胱造口。
9例患者(3例女性,6例男性。平均年龄74.1岁;57至87岁)的RACIC手术在技术上均获成功,无需中转开放手术。包括扩大盆腔淋巴结清扫术和尿流改道术在内的平均手术时间为346.2分钟(210至480分钟)。尿流改道术的平均手术时间为72分钟(52 - 113分钟),平均估计失血量为258毫升(200至500毫升),中位住院时间为14天(10至27天)。3例女性患者均经阴道取出标本。术中无并发症发生,术后仅出现1例严重并发症:1例男性患者术后因操作不当牵拉器官袋,可能损伤回肠膀胱蒂部,导致回肠膀胱医源性坏死,因手术结束时回肠膀胱血运良好,需行开放手术修复(该男性患者经耻骨上切口取出标本)。术后第3天开始进清流饮食。所有患者在2周内(自手术之日起)恢复正常活动。术后肾功能正常,术后平均肌酐为0.99毫克/分升,排泄性尿路造影显示所有病例上尿路均无梗阻。
机器人辅助根治性膀胱前列腺切除术联合全体内置回肠膀胱尿流改道术治疗高危或浸润性膀胱癌伴尿流改道在技术上是可行的。机器人系统有助于进行精细解剖,能精确复制开放手术的所有操作步骤,同时遵循传统根治性膀胱切除术的可靠肿瘤学原则。机器人技术带来了前所未有的手术器械操控性,缩短了学习曲线,使开放手术医生能够更轻松地以微创方式应用其技术技能。机器人辅助全体内置回肠膀胱尿流改道术膀胱切除术具有手术及围手术期优势和功能结局。在我们的经验中,其结果与开放手术相当,且围手术期发病率进一步降低、恢复早、能恢复正常活动、美容效果极佳并提高了生活质量(QOL)。此外,术中失血少、液体转移及电解质丢失少,极大地减轻了这些老年患者群体的全身及心血管应激反应。