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肾肿瘤肾部分切除术的结果,肾肿瘤的肾肿瘤评分≥7。

Outcomes of robotic partial nephrectomy for renal masses with nephrometry score of ≥7.

机构信息

Department of Surgery, Center for Laparoscopic and Robotic Surgery, Glickman Urological and Kidney Institute, 9500 Euclid Avenue, Q-10, Cleveland, OH 44195, USA.

出版信息

Urology. 2011 Apr;77(4):809-13. doi: 10.1016/j.urology.2010.12.005. Epub 2011 Feb 18.

Abstract

OBJECTIVES

To evaluate the safety and feasibility of robotic partial nephrectomy for patients with complex renal masses.

METHODS

We reviewed the data for 164 consecutive patients who had undergone transperitoneal robotic partial nephrectomy at a tertiary care center from February 2007 to June 2010. Of the 112 patients who had available imaging studies to review, 67 were identified and classified as having a moderately or highly complex renal mass according to the R.E.N.A.L. nephrometry score (≥7) (tumor size-[R]adius, location and depth-[E]xophytic or endophytic; nearness to the renal sinus fat or collecting system [N]; anterior or posterior position [A], and polar vs non-polar location [L]). The preoperative, perioperative, pathologic, and functional outcomes data were analyzed.

RESULTS

The median body mass index was 29.6 kg/m(2) (range 19.9-44.8). Of the 67 patients, 32 were men and 35 were women, with 32 right-sided masses and 35 left-sided masses. The median tumor size was 3.7 cm (range 1.2-11), and the median operative time was 180 minutes (range 150-180). The median estimated blood loss was 200 mL (range 100-375), and the warm ischemia time was 19.0 minutes (range 15-26). The median hospital stay was 3.0 days (range 3-4). The estimated glomerular filtration rate was calculated at a median decrease of 11.1 mL/min/1.73 m(2) (range 9-1.3). According to the Clavien-Dindo classification of surgical complications, 2 grade 1, 12 grade 2, and 1 grade 3 complication occurred. All margins were pathologically negative, except for 1, and, after a mean follow-up of 10 months, no recurrences had developed.

CONCLUSIONS

Robotic partial nephrectomy is a safe and feasible option for moderately or highly complex renal masses determined by the R.E.N.A.L. nephrometry score. The warm ischemia time, blood loss, and complications were increased with highly complex masses.

摘要

目的

评估机器人辅助部分肾切除术治疗复杂肾肿瘤患者的安全性和可行性。

方法

我们回顾了 2007 年 2 月至 2010 年 6 月在一家三级医疗中心接受经腹腔机器人辅助部分肾切除术的 164 例连续患者的数据。在可进行影像学检查的 112 例患者中,有 67 例根据 R.E.N.A.L. 肾肿瘤测量评分(≥7)被确定为具有中度或高度复杂肾肿瘤(肿瘤大小-[R]adius,位置和深度-[E]xophytic 或 endophytic;靠近肾窦脂肪或收集系统 [N];前位或后位 [A],极性与非极性位置 [L])。分析了术前、围手术期、病理和功能结果数据。

结果

中位体重指数为 29.6kg/m2(范围 19.9-44.8)。67 例患者中,32 例为男性,35 例为女性,32 例为右侧肿块,35 例为左侧肿块。肿瘤中位大小为 3.7cm(范围 1.2-11),中位手术时间为 180 分钟(范围 150-180)。中位估计失血量为 200mL(范围 100-375),热缺血时间为 19.0 分钟(范围 15-26)。中位住院时间为 3.0 天(范围 3-4)。估算肾小球滤过率中位数下降 11.1mL/min/1.73m2(范围 9-1.3)。根据 Clavien-Dindo 手术并发症分级,2 级 1 例,12 级 2 例,1 级 3 例。所有边缘均为病理阴性,除 1 例外,平均随访 10 个月后无复发。

结论

对于 R.E.N.A.L. 肾肿瘤测量评分确定的中度或高度复杂肾肿瘤,机器人辅助部分肾切除术是一种安全可行的选择。热缺血时间、出血量和并发症随高度复杂肿瘤而增加。

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