Department of Physical Therapy, Leiden University Medical Center, Leiden, The Netherlands.
J Surg Oncol. 2011 Mar 1;103(3):276-82. doi: 10.1002/jso.21828. Epub 2010 Dec 28.
Aim of our study was to compare functional ability and physical activity in children and young adults who underwent surgery for a malignant bone tumor that was located around the knee.
This cross-sectional study included 82 patients aged 8-25 years with a follow-up of 1-5 years. The functional ability and the amount of physical activity were evaluated by means of questionnaires and objective instruments.
Thirty nine patients underwent limb-salvage surgery (24 allograft and 15 endoprosthesis) and 43 underwent ablative surgery (27 amputations and 16 rotationplasty). Patients in the limb-salvage group were significantly older at the time of surgery than patients in the ablative group (mean age 15.2 years vs. 13.2 years, P = 0.03). Apart from significantly better scores for the timed up and down stairs and various walking activities in the limb-salvage group as compared to the ablative surgery group, no significant differences were seen for any of the outcome measures.
One to 5 years after limb-salvage and ablative surgery due to a malignant bone tumor children and young adults do, apart from a few activities involving walking and climbing stairs, not differ with respect to overall functional ability and physical activity.
本研究的目的是比较儿童和青少年因膝关节周围恶性骨肿瘤而接受手术治疗后的功能能力和身体活动情况。
本横断面研究纳入了 82 名年龄在 8 至 25 岁之间、随访时间为 1 至 5 年的患者。通过问卷调查和客观仪器评估功能能力和身体活动量。
39 名患者接受了保肢手术（24 例异体骨移植和 15 例人工假体置换），43 名患者接受了截肢手术（27 例截肢和 16 例旋转成形术）。保肢组患者的手术年龄明显大于截肢组（平均年龄 15.2 岁比 13.2 岁，P = 0.03）。除了保肢组在上下楼梯和各种步行活动的计时测试中得分明显高于截肢组外，在任何其他结果测量中均未见明显差异。
儿童和青少年因恶性骨肿瘤接受保肢和截肢手术后 1 至 5 年，除了涉及行走和爬楼梯的少数活动外，其整体功能能力和身体活动没有差异。
