Bollati Mario, Gaita Fiorenzo, Anselmino Matteo
Department of Internal Medicine, Division of Cardiology, University of Torino, Italy.
Vasc Health Risk Manag. 2011 Jan 12;7:23-30. doi: 10.2147/VHRM.S12271.
Antiplatelet therapy plays a fundamental role in reducing atherothrombotic events by several pathways. The present work reviews available evidence on antiplatelet therapy both for primary prevention and in the presence of established peripheral, cerebral, or cardiac ischemic disease. Due to the importance of adherence to therapy to achieve optimal effects, special attention is given to the use of fixed-dose oral formulations in the clinical subset of patients in whom double antiplatelet therapy has proven indications.
抗血小板治疗通过多种途径在减少动脉粥样硬化血栓形成事件中发挥着重要作用。本研究综述了抗血小板治疗在一级预防以及已确诊的外周、脑或心脏缺血性疾病中的现有证据。由于坚持治疗对于实现最佳疗效至关重要，因此特别关注在已证实有双重抗血小板治疗指征的临床亚组患者中使用固定剂量口服制剂的情况。
